HitPredict

Interactor 1: TNIK (P83510)
Traf2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Interactor 2: FXR1 (Q61584)
RNA-binding protein FXR1 (FXR1P) (mFxr1p)
Gene: FXR1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0048471 - perinuclear region of cytoplasm GO:0098793 - presynapse GO:0098978 - glutamatergic synapse
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1323 Mm			1 677
+	Mm
		949318 TNIK_MOUSE (1-1323): 0: 1277: 100.00		Q6P5B5_MOUSE (4-656): 0: 861: 63.81
+	Mm
		949430 TNIK_MOUSE (1-1323): 0: 1277: 100.00		FXR2_MOUSE (4-656): 0: 830: 62.46
+	Mm
		956962 M4K4_MOUSE (1-1323): 0: 992: 59.97		FXR1_MOUSE (1-677): 0: 1073: 100.00
+	Mm
		949360 TNIK_MOUSE (1-1323): 0: 1277: 100.00		Q8BPK8_MOUSE (1-334): 0: 622: 73.65
+	Mm
		956968 M4K4_MOUSE (1-1323): 0: 992: 59.97		Q8BPK8_MOUSE (1-334): 0: 622: 73.65
+	Mm
		729453 TNIK_MOUSE (1-1323): 0: 1277: 100.00		FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80
+	Mm
		729456 M4K4_MOUSE (1-1323): 0: 992: 59.97		FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80
+	Hs
		159196 CSKP_HUMAN (22-702): 1.09e-122: 405: 15.80		FMR1_HUMAN (300-461): 3.4e-48: 181: 56.10
+	Hs
		988940 MRCKA_HUMAN (15-710): 6.29e-108: 378: 15.12		FMR1_HUMAN (300-461): 3.4e-48: 181: 56.10