HitPredict

Interactor 1: CBX1 (P83916)
Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)
Gene: CBX1

Interactor 2: CBX1 (P83916)
Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)
Gene: CBX1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.853

The method score is based on:

Property Details
Experiments 11336697, 16615912, 21888893
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, molecular sieving
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Chromo~Chromo, Chromo_shadow~Chromo_shadow
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000775 - chromosome, centromeric region
GO:0000781 - chromosome, telomeric region
GO:0000785 - chromatin
GO:0000792 - heterochromatin
and 16 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 185
Hs

1 185
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024