HitPredict

Interactor 1: CBX1 (P83916)
Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)
Gene: CBX1

Interactor 2: ADNP (Q9H2P0)
Activity-dependent neuroprotector homeobox protein (Activity-dependent neuroprotective protein)
Gene: ADNP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.723

Property	Details
Experiments	24981860, 20850016, 27705803, 35271311, 21888893
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 185 Hs			1 1102
+	Hs
		1027253 CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49		ADNP_HUMAN (1-1102): 0: 1877: 100.00
+	Hs
		800523 CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45		ADNP_HUMAN (1-1102): 0: 1877: 100.00
+	Mm
		1169697 Q9DCC5_MOUSE (1-177): 2.11e-63: 195: 69.49		Q6ZQ47_MOUSE (20-1102): 0: 1867: 93.49
+	Mm
		949944 CBX1_MOUSE (1-185): 2.21e-62: 193: 100.00		Q6ZQ47_MOUSE (20-1102): 0: 1867: 93.49
+	Mm
		1143028 CBX5_MOUSE (1-183): 7.63e-60: 186: 57.98		Q6ZQ47_MOUSE (20-1102): 0: 1867: 93.49
+	Hs
		1027053 CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49		ADNP2_HUMAN (1-413): 5.4e-145: 466: 27.87
+	Hs
		949813 CBX1_HUMAN (1-185): 2.21e-62: 193: 100.00		ADNP2_HUMAN (1-413): 5.4e-145: 466: 27.87
+	Hs
		800419 CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45		ADNP2_HUMAN (1-413): 5.4e-145: 466: 27.87
+	Mm
		1208472 Q9DCC5_MOUSE (1-177): 2.11e-63: 195: 69.49		ADNP2_MOUSE (1-421): 2.25e-137: 446: 27.75
+	Mm
		949955 CBX1_MOUSE (1-185): 2.21e-62: 193: 100.00		ADNP2_MOUSE (1-421): 2.25e-137: 446: 27.75