HitPredict

Interactor 1: SMAD3 (P84022)
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (hMAD-3) (JV15-2) (SMAD family member 3) (SMAD 3) (Smad3) (hSMAD3)
Gene: SMAD3

Interactor 2: ZMY11 (Q15326)
Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A-binding protein) (Bone morphogenetic protein receptor-associated molecule 1) (Protein BS69)
Gene: ZMYND11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21988832
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 425 Hs			1 602
+	Hs
		1071463 SMAD2_HUMAN (1-425): 0: 589: 83.73		ZMY11_HUMAN (1-602): 0: 607: 100.00
+	Hs
		170332 SMAD3_HUMAN (1-425): 0: 636: 100.00		TIF1A_HUMAN (90-301): 1.95e-44: 172: 20.25
+	Hs
		950328 SMAD3_HUMAN (1-425): 0: 636: 100.00		TRI33_HUMAN (57-304): 9.89e-41: 160: 16.67
+	Hs
		950237 SMAD3_HUMAN (1-425): 0: 636: 100.00		KAT2B_HUMAN (122-254): 2.57e-31: 131: 17.78
+	Hs
		1078697 SMAD2_HUMAN (1-425): 0: 589: 83.73		TRI33_HUMAN (57-304): 9.89e-41: 160: 16.67
+	Hs
		600125 SMAD3_HUMAN (1-425): 0: 636: 100.00		TAF1_HUMAN (129-459): 1.13e-24: 111: 12.20
+	Hs
		950158 SMAD3_HUMAN (1-425): 0: 636: 100.00		BPTF_HUMAN (85-557): 3.83e-16: 84.7: 13.15
+	Hs
		1078608 SMAD2_HUMAN (1-425): 0: 589: 83.73		KAT2B_HUMAN (122-254): 2.57e-31: 131: 17.78
+	Hs
		1029463 SMAD2_HUMAN (1-425): 0: 589: 83.73		TIF1B_HUMAN (76-254): 7.94e-31: 130: 14.29
+	Hs
		950236 SMAD3_HUMAN (1-425): 0: 636: 100.00		KAT2A_HUMAN (146-254): 6.58e-14: 77.2: 22.02
+	Hs
		600150 SMAD2_HUMAN (1-425): 0: 589: 83.73		TAF1_HUMAN (129-459): 1.13e-24: 111: 12.20
+	Mm
		936623 SMAD1_MOUSE (1-425): 0: 560: 59.87		KAT2B_MOUSE (122-254): 1.24e-31: 132: 18.52
+	Hs
		171425 SMAD9_HUMAN (1-425): 0: 559: 58.62		KAT2B_HUMAN (122-254): 2.57e-31: 131: 17.78
+	Hs
		1017303 SMAD2_HUMAN (1-425): 0: 589: 83.73		BPTF_HUMAN (85-557): 3.83e-16: 84.7: 13.15
+	Hs
		600151 SMAD1_HUMAN (1-425): 0: 559: 60.09		TAF1_HUMAN (129-459): 1.13e-24: 111: 12.20
+	Hs
		1078607 SMAD2_HUMAN (1-425): 0: 589: 83.73		KAT2A_HUMAN (146-254): 6.58e-14: 77.2: 22.02
+	Hs
		1078736 SMAD1_HUMAN (1-425): 0: 559: 60.09		KAT2A_HUMAN (146-254): 6.58e-14: 77.2: 22.02
+	Hs
		171424 SMAD9_HUMAN (1-425): 0: 559: 58.62		KAT2A_HUMAN (146-254): 6.58e-14: 77.2: 22.02
+	Hs
		1271444 SMAD5_HUMAN (1-425): 0: 556: 59.83		KAT2A_HUMAN (146-254): 6.58e-14: 77.2: 22.02
+	Xl
		1122749 Q9W639_XENLA (23-414): 3.81e-131: 390: 35.71		TRI33_XENLA (99-255): 5.7e-41: 161: 18.78