HitPredict

Interactor 1: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Interactor 2: CYFP1 (Q7L576)
Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1)
Gene: CYFIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0008360 - regulation of cell shape GO:0016601 - Rac protein signal transduction GO:0070062 - extracellular exosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 1253
+	Hs
		925386 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Mm
		925800 RAC1_MOUSE (1-191): 3.6e-82: 243: 71.88		CYFP1_MOUSE (1-1253): 0: 2079: 99.04
+	Hs
		545463 RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		894162 CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		900624 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		925513 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		892449 RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		951231 RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Mm
		1143609 RHOC_MOUSE (5-191): 8.34e-77: 230: 56.15		CYFP1_MOUSE (1-1253): 0: 2079: 99.04
+	Hs
		545555 RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		900789 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		892535 RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Dm
		776913 RAC1_DROME (1-191): 5.32e-79: 235: 67.71		CYFIP_DROME (1-1253): 0: 1903: 65.73
+	At
		1105123 RAC3_ARATH (2-180): 7.36e-92: 268: 56.98		PIR_ARATH (5-1240): 0: 1535: 28.88