Protein: CADH2
Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325)

Gene: CADH2, CDH2
Organism: Homo sapiens
Interactions: 120
UniProt ID: P19022

Gene Ontology (top 5):
GO:0000902 - cell morphogenesis
GO:0003323 - type B pancreatic cell development
GO:0003723 - RNA binding
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

618223

CTNB1
Catenin beta-1

20

20

Small-scale

0.987

High

254049

CTND1
Catenin delta-1

8

20

Small-scale

0.961

High

577607

PLAK
Junction plakoglobin

4

20

Small-scale

0.886

High

618222

CTNA1
Catenin alpha-1

5

20

Small-scale

0.709

High

125876

ARVC
Splicing regulator ARVCF

1

20

High-throughput

0.691

High

618274

CLC4D
C-type lectin domain family 4 member D

1

14

High-throughput

0.665

High

618294

CTNA3
Catenin alpha-3

2

20

High-throughput

0.628

High

618282

PKP4
Plakophilin-4

1

20

Small-scale

0.621

High

463899

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

High-throughput

0.618

High

618233

CADH4
Cadherin-4

1

16

Small-scale

0.618

High

618234

CAD11
Cadherin-11

1

18

Small-scale

0.618

High

504704

FBSP1
F-box/SPRY domain-containing protein 1

2

20

Small-scale

0.611

High

618258

DDR2
Discoidin domain-containing receptor 2

2

20

Small-scale

0.611

High

167493

TX1B3
Tax1-binding protein 3

2

14

High-throughput

0.601

High

618275

CBP
CREB-binding protein

2

6

Small-scale

0.595

High

540307

LAMP1
Lysosome-associated membrane glycoprotein 1

2

6

High-throughput

0.588

High

362744

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.584

High

410606

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

20

Small-scale

0.584

High

541326

FGFR1
Fibroblast growth factor receptor 1

2

20

Small-scale

0.584

High

618264

CLC4G
C-type lectin domain family 4 member G

1

15

Small-scale

0.575

High

618298

PCDGD
Protocadherin gamma-B1

1

20

High-throughput

0.575

High

618280

LRRC7
Leucine-rich repeat-containing protein 7

1

3

Small-scale

0.561

High

529043

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.536

High

618218

CALX
Calnexin

1

7

High-throughput

0.536

High

618256

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.536

High

137179

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.518

High

188812

TMPS2
Transmembrane protease serine 2

1

11

High-throughput

0.515

High

618217

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.515

High

618292

TMPS4
Transmembrane protease serine 4

1

11

High-throughput

0.515

High

507510

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

High-throughput

0.501

High

618244

GNA12
Guanine nucleotide-binding protein subunit alpha-12

1

5

Small-scale

0.501

High

618251

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

5

Small-scale

0.501

High

618228

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

7

Small-scale

0.500

High

618246

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

20

High-throughput

0.500

High

618252

NAA25
N-alpha-acetyltransferase 25, NatB auxiliary subunit

1

10

Small-scale

0.500

High

349652

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

1

1

High-throughput

0.489

High

618262

SAPC1
Suppressor APC domain-containing protein 1

1

1

High-throughput

0.489

High

618277

SPSB4
SPRY domain-containing SOCS box protein 4

1

20

High-throughput

0.489

High

618295

HECD1
E3 ubiquitin-protein ligase HECTD1

1

4

High-throughput

0.489

High

125218

LEG9
Galectin-9

1

4

High-throughput

0.479

High

126459

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

217811

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.479

High

245781

PI51C
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma

1

2

Small-scale

0.479

High

293178

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.479

High

376475

LDLR
Low-density lipoprotein receptor

1

2

High-throughput

0.479

High

411328

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

465401

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.479

High

466102

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

471982

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.479

High

530992

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

19

High-throughput

0.479

High

538368

EGR2
E3 SUMO-protein ligase EGR2

1

4

High-throughput

0.479

High

580867

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

614647

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

20

High-throughput

0.479

High

618214

CCNA2
Cyclin-A2

1

3

Small-scale

0.479

High

618219

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.479

High

618221

RYK
Tyrosine-protein kinase RYK

1

20

Small-scale

0.479

High

618225

BASI
Basigin

1

7

High-throughput

0.479

High

618226

BMR1A
Bone morphogenetic protein receptor type-1A

1

11

High-throughput

0.479

High

618229

PSN1
Presenilin-1

1

6

Small-scale

0.479

High

618231

EPHA4
Ephrin type-A receptor 4

1

20

High-throughput

0.479

High

618236

SC61B
Protein transport protein Sec61 subunit beta

1

2

High-throughput

0.479

High

618237

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

618238

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

618239

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

618241

ACTS
Actin, alpha skeletal muscle

1

1

Small-scale

0.479

High

618242

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.479

High

618243

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

618247

DDR1
Epithelial discoidin domain-containing receptor 1

1

20

Small-scale

0.479

High

618250

CUL4A
Cullin-4A

1

8

High-throughput

0.479

High

618255

EPHA7
Ephrin type-A receptor 7

1

20

High-throughput

0.479

High

618259

CDON
Cell adhesion molecule-related/down-regulated by oncogenes

1

4

Small-scale

0.479

High

618260

MIDN
Midnolin

1

1

High-throughput

0.479

High

618266

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

618268

TM11B
Transmembrane protease serine 11B

1

11

High-throughput

0.479

High

618272

PARD3
Partitioning defective 3 homolog

1

12

High-throughput

0.479

High

618276

RAB8B
Ras-related protein Rab-8B

1

7

Small-scale

0.479

High

618285

DUS26
Dual specificity protein phosphatase 26

1

2

Small-scale

0.479

High

618286

BOC
Brother of CDO

1

9

Small-scale

0.479

High

618287

ACE2
Angiotensin-converting enzyme 2

1

3

Small-scale

0.479

High

618289

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

618290

PKHA4
Pleckstrin homology domain-containing family A member 4

1

19

High-throughput

0.479

High

618291

FBX6
F-box only protein 6

1

2

High-throughput

0.479

High

618293

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

618227

HPCL1
Hippocalcin-like protein 1

1

0

Small-scale

0.458

High

618230

BAP31
B-cell receptor-associated protein 31

1

0

Small-scale

0.458

High

618240

SKP1
S-phase kinase-associated protein 1

1

0

Small-scale

0.458

High

471719

PTPRC
Receptor-type tyrosine-protein phosphatase C

1

20

High-throughput

0.445

High

480695

LEG1
Galectin-1

1

4

High-throughput

0.445

High

618215

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

20

High-throughput

0.445

High

618216

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

20

High-throughput

0.445

High

618220

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

20

High-throughput

0.445

High

618224

PTN7
Tyrosine-protein phosphatase non-receptor type 7

1

20

High-throughput

0.445

High

618232

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.445

High

618235

CD81
CD81 antigen

1

3

High-throughput

0.445

High

618245

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

20

High-throughput

0.445

High

618248

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

20

High-throughput

0.445

High

618249

CUL3
Cullin-3

1

8

High-throughput

0.445

High

618253

PTPRR
Receptor-type tyrosine-protein phosphatase R

1

20

High-throughput

0.445

High

618254

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

20

High-throughput

0.445

High

618257

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

20

High-throughput

0.445

High

618263

LRC8B
Volume-regulated anion channel subunit LRRC8B

1

4

High-throughput

0.445

High

618265

ZNT10
Calcium/manganese antiporter SLC30A10

1

12

High-throughput

0.445

High

618267

NIPA1
Magnesium transporter NIPA1

1

2

High-throughput

0.445

High

618270

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.445

High

618271

ZNT7
Zinc transporter 7

1

12

High-throughput

0.445

High

618281

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

7

High-throughput

0.445

High

618296

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.445

High

618297

PTN22
Tyrosine-protein phosphatase non-receptor type 22

1

20

High-throughput

0.445

High

105299

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

371124

MYC
Myc proto-oncogene protein

1

12

High-throughput

0.437

High

618288

FOXQ1
Forkhead box protein Q1

1

2

Small-scale

0.437

High

469457

SYPH
Synaptophysin

1

0

High-throughput

0.426

High

618269

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

Small-scale

0.426

High

618273

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.426

High

618261

NTCP5
Sodium/bile acid cotransporter 5

1

2

High-throughput

0.407

High

618278

AURKB
Aurora kinase B

1

8

High-throughput

0.407

High

618279

MF14A
Hippocampus abundant transcript 1 protein

1

3

High-throughput

0.407

High

618283

ZBT18
Zinc finger and BTB domain-containing protein 18

1

2

High-throughput

0.407

High

618284

SPSB2
SPRY domain-containing SOCS box protein 2

1

19

High-throughput

0.407

High

342506

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025