Interactor 1: PTEN (P60484)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)
Gene: PTEN

Interactor 2: SHRM3 (Q8TF72)
Protein Shroom3 (Shroom-related protein) (hShrmL)
Gene: SHROOM3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 30631154, 37839992
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0016324 - apical plasma membrane
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 403
Hs

1 1996
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025