Protein: TENS1
Tensin-1 (EC 3.1.3.-)

Gene: TENS1, TNS1
Organism: Homo sapiens
Interactions: 53
UniProt ID: Q9HBL0

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003779 - actin binding
GO:0004721 - phosphoprotein phosphatase activity
GO:0005737 - cytoplasm
GO:0005856 - cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

834232

CSK
Tyrosine-protein kinase CSK

2

19

High-throughput

0.789

High

250341

VINEX
Vinexin

2

10

High-throughput

0.776

High

472129

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

1106510

GAB1
GRB2-associated-binding protein 1

1

6

High-throughput

0.692

High

1104878

SNTB2
Beta-2-syntrophin

1

20

High-throughput

0.691

High

1118453

SNTB1
Beta-1-syntrophin

1

20

High-throughput

0.691

High

363883

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.647

High

990757

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.621

High

532103

KIT
Mast/stem cell growth factor receptor Kit

1

14

High-throughput

0.619

High

401513

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

8

High-throughput

0.618

High

942896

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

12

Small-scale

0.618

High

1224913

TENS2
Tensin-2

1

14

High-throughput

0.618

High

1255613

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.618

High

547485

DMD
Dystrophin

2

20

High-throughput

0.601

High

1433310

WNK1
Serine/threonine-protein kinase WNK1

1

10

High-throughput

0.590

High

184324

NPHP1
Nephrocystin-1

1

0

Small-scale

0.586

High

411064

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.579

High

641679

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.579

High

787081

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

12

Small-scale

0.579

High

1145782

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.579

High

220305

FRS3
Fibroblast growth factor receptor substrate 3

2

1

High-throughput

0.576

High

691449

1433T
14-3-3 protein theta

1

20

High-throughput

0.575

High

730259

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.575

High

520383

ANDR
Androgen receptor

1

12

High-throughput

0.536

High

262435

DTNB
Dystrobrevin beta

1

11

High-throughput

0.536

High

858810

BRCC3
Lys-63-specific deubiquitinase BRCC36

1

3

High-throughput

0.536

High

862712

UTRN
Utrophin

1

19

High-throughput

0.536

High

1119657

KCNC3
Voltage-gated potassium channel KCNC3

1

2

High-throughput

0.536

High

1136948

ABRX2
BRISC complex subunit Abraxas 2

1

3

High-throughput

0.536

High

1438328

BABA1
BRISC and BRCA1-A complex member 1

1

1

High-throughput

0.536

High

1438330

CTNL1
Alpha-catulin

1

4

High-throughput

0.536

High

440737

FYN
Tyrosine-protein kinase Fyn

1

16

High-throughput

0.514

High

786859

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

6

Small-scale

0.508

High

1095104

KLF10
Krueppel-like factor 10

1

2

High-throughput

0.508

High

1400677

RHG07
Rho GTPase-activating protein 7

1

8

Small-scale

0.506

High

1438327

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.486

High

1045787

TF65
Transcription factor p65

1

4

High-throughput

0.479

High

1438329

HDAC6
Protein deacetylase HDAC6

1

5

High-throughput

0.479

High

386251

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

5

High-throughput

0.470

High

253985

LPXN
Leupaxin

1

12

High-throughput

0.445

High

1177197

MICB
MHC class I polypeptide-related sequence B

1

1

High-throughput

0.445

High

1438332

GPSM3
G-protein-signaling modulator 3

1

1

High-throughput

0.445

High

106673

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

377729

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

2

High-throughput

0.437

High

551272

PCNA
Proliferating cell nuclear antigen

1

2

High-throughput

0.437

High

965255

WDR5
WD repeat-containing protein 5

1

3

High-throughput

0.437

High

606039

CAN2
Calpain-2 catalytic subunit

1

0

Small-scale

0.426

High

946588

EVA1C
Protein eva-1 homolog C

1

1

High-throughput

0.407

High

1258588

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

2

High-throughput

0.407

High

1437947

ELL3
RNA polymerase II elongation factor ELL3

1

3

High-throughput

0.407

High

1438331

FBW1B
F-box/WD repeat-containing protein 11

1

10

High-throughput

0.407

High

1256795

LHPL2
LHFPL tetraspan subfamily member 2 protein

1

0

High-throughput

0.232

Low

1381165

SNX21
Sorting nexin-21

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025