HitPredict

Interactor 1: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Interactor 2: PCBP2 (Q15366)
Poly(rC)-binding protein 2 (Alpha-CP2) (Heterogeneous nuclear ribonucleoprotein E2) (hnRNP E2)
Gene: PCBP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.529

Property	Details
Experiments	17183366
Identification Methods	anti bait coimmunoprecipitation, two hybrid, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 164 Hs			1 365
+	Hs
		266997 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		PCBP2_HUMAN (1-365): 6.73e-117: 345: 100.00
+	Hs
		853901 NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14		PCBP2_HUMAN (1-365): 6.73e-117: 345: 100.00
+	Mm
		904289 SRSF7_MOUSE (7-115): 1.47e-26: 102: 60.55		HNRPK_MOUSE (10-361): 2.75e-76: 244: 26.17
+	Hs
		903884 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		HNRPK_HUMAN (10-361): 2.75e-76: 244: 26.17
+	Mm
		904238 SRSF3_MOUSE (1-164): 6.39e-27: 100: 100.00		HNRPK_MOUSE (10-361): 2.75e-76: 244: 26.17
+	Mm
		904278 SRSF1_MOUSE (9-80): 1.1e-25: 100: 48.65		HNRPK_MOUSE (10-361): 2.75e-76: 244: 26.17
+	Mm
		192620 SRSF5_MOUSE (10-112): 1.98e-24: 97: 44.34		HNRPK_MOUSE (10-361): 2.75e-76: 244: 26.17
+	Mm
		904361 SRS10_MOUSE (1-164): 2.25e-24: 96.6: 32.54		HNRPK_MOUSE (10-361): 2.75e-76: 244: 26.17
+	Hs
		853838 NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14		HNRPK_HUMAN (10-361): 2.75e-76: 244: 26.17
+	Zm
		20647 A0A1D6HMW8_MAIZE (10-85): 2.32e-24: 96.3: 36.70		B6U784_MAIZE (16-351): 9.75e-17: 83.7: 17.33
+	Hs
		853956 NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14		FUBP2_HUMAN (282-364): 1.14e-16: 83.3: 30.12
+	Dm
		2536 Q9VYD8_DROME (7-80): 2.07e-25: 97: 70.27		NOVA_DROME (13-191): 2.69e-14: 76.3: 30.16
+	Hs
		1028764 SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34		FUBP1_HUMAN (216-362): 1.11e-13: 74.1: 19.73
+	Mm
		888818 SRSF7_MOUSE (7-115): 1.47e-26: 102: 60.55		PCBP1_MOUSE (93-173): 3.7e-12: 68.7: 28.40
+	Hs
		1031431 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		FUBP3_HUMAN (244-362): 8.21e-15: 77.6: 22.69
+	Mm
		888801 SRSF3_MOUSE (1-164): 6.39e-27: 100: 100.00		PCBP1_MOUSE (93-173): 3.7e-12: 68.7: 28.40
+	Hs
		951974 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		PCBP1_HUMAN (93-173): 3.7e-12: 68.7: 28.40
+	Hs
		1031417 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		FUBP1_HUMAN (216-362): 1.11e-13: 74.1: 19.73
+	Hs
		884293 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		PCBP3_HUMAN (264-358): 5.07e-11: 65.2: 23.16
+	Hs
		853900 NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14		PCBP1_HUMAN (93-173): 3.7e-12: 68.7: 28.40