HitPredict

Interactor 1: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Interactor 2: RMXL1 (Q96E39)
RNA binding motif protein, X-linked-like-1 (Heterogeneous nuclear ribonucleoprotein G-like 1)
Gene: RBMXL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 164 Hs			1 390
+	Hs
		1084363 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		RMXL1_HUMAN (1-357): 3.75e-42: 153: 100.00
+	Hs
		745125 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		RBMX_HUMAN (1-390): 4.19e-44: 158: 92.07
+	Hs
		266929 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		RBMX_HUMAN (1-390): 4.19e-44: 158: 92.07
+	Hs
		992876 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		RMXL1_HUMAN (1-357): 3.75e-42: 153: 100.00
+	Hs
		1084450 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		PPIE_HUMAN (10-96): 1.17e-30: 120: 39.08
+	Zm
		18728 A0A1D6H7I7_MAIZE (10-163): 3.59e-27: 105: 29.59		O48554_MAIZE (1-85): 1.85e-33: 123: 42.35
+	Hs
		952193 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		RBM7_HUMAN (2-268): 6.54e-33: 126: 22.68
+	Hs
		951962 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		CIRBP_HUMAN (4-145): 3.72e-32: 120: 45.70
+	Hs
		952176 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		PPIE_HUMAN (10-96): 1.17e-30: 120: 39.08
+	Hs
		1028873 SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34		PPIE_HUMAN (10-96): 1.17e-30: 120: 39.08
+	Hs
		951937 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		ELAV2_HUMAN (2-133): 2.03e-23: 101: 24.09
+	Hs
		992743 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		ELAV2_HUMAN (2-133): 2.03e-23: 101: 24.09
+	Hs
		266976 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		ELAV2_HUMAN (2-133): 2.03e-23: 101: 24.09
+	Hs
		1054347 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		RBM39_HUMAN (3-112): 6.61e-15: 77.9: 22.73
+	Hs
		680437 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		TIA1_HUMAN (2-353): 1.72e-18: 88: 14.25
+	Mm
		857340 SRSF1_MOUSE (9-80): 1.1e-25: 100: 48.65		TIA1_MOUSE (2-344): 1.69e-18: 88: 14.59
+	Hs
		951964 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		RBM39_HUMAN (3-112): 6.61e-15: 77.9: 22.73
+	Hs
		992769 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		RBM39_HUMAN (3-112): 6.61e-15: 77.9: 22.73
+	Hs
		951924 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		RBM3_HUMAN (8-88): 1.05e-15: 75.9: 55.56
+	Hs
		266990 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		RBM39_HUMAN (3-112): 6.61e-15: 77.9: 22.73