HitPredict

Interactor 1: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Interactor 2: DHX36 (Q9H2U1)
ATP-dependent DNA/RNA helicase DHX36 (EC 3.6.4.12) (EC 3.6.4.13) (DEAD/H box polypeptide 36) (DEAH-box protein 36) (G4-resolvase-1) (G4R1) (MLE-like protein 1) (RNA helicase associated with AU-rich element protein)
Gene: DHX36

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 164 Hs			1 1008
+	Hs
		1084405 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		DHX36_HUMAN (1-1008): 0: 1048: 100.00
+	Hs
		992927 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		DHX36_HUMAN (1-1008): 0: 1048: 100.00
+	Hs
		1028815 SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34		DHX36_HUMAN (1-1008): 0: 1048: 100.00
+	Hs
		1055380 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		DHX8_HUMAN (4-951): 0: 835: 21.18
+	Hs
		992770 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		DHX8_HUMAN (4-951): 0: 835: 21.18
+	Bt
		898864 PABP1_BOVIN (1-91): 1.13e-20: 89.6: 25.77		DHX9_BOVIN (57-1005): 0: 839: 33.02
+	Hs
		994318 RBM4_HUMAN (11-88): 3.45e-18: 81.9: 28.21		DHX9_HUMAN (57-1005): 0: 841: 33.02
+	Hs
		992812 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		DHX57_HUMAN (68-990): 0: 805: 38.48
+	Hs
		1028697 SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34		DHX57_HUMAN (68-990): 0: 805: 38.48
+	Sc
		376861 PABP_YEAST (2-93): 6.85e-19: 84.2: 20.62		PRP43_YEAST (123-915): 0: 806: 27.79
+	Hs
		1084313 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		DHX30_HUMAN (187-963): 0: 764: 35.38
+	Hs
		195383 NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14		DHX15_HUMAN (178-934): 0: 770: 23.54
+	Hs
		952009 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		DHX30_HUMAN (187-963): 0: 764: 35.38
+	Hs
		992826 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		DHX30_HUMAN (187-963): 0: 764: 35.38
+	Hs
		1028710 SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34		DHX30_HUMAN (187-963): 0: 764: 35.38
+	Hs
		853931 NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14		DHX30_HUMAN (187-963): 0: 764: 35.38
+	Hs
		1184003 RBM4B_HUMAN (11-88): 5.29e-18: 81.1: 28.21		DHX30_HUMAN (187-963): 0: 764: 35.38
+	Hs
		1049417 CSTFT_HUMAN (10-110): 1.69e-24: 100: 24.53		DHX34_HUMAN (187-865): 2.69e-104: 353: 32.26
+	Sc
		376941 PABP_YEAST (2-93): 6.85e-19: 84.2: 20.62		YL419_YEAST (184-964): 1.39e-97: 338: 29.97
+	Sc
		376924 PABP_YEAST (2-93): 6.85e-19: 84.2: 20.62		DHR1_YEAST (127-732): 2.19e-70: 258: 29.38