HitPredict

Interactor 1: H32 (P84228)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (H3-clustered histone 2) (H3-clustered histone 3) (H3-clustered histone 4) (H3-clustered histone 6) (H3-clustered histone 7)
Gene: H3c2

Interactor 2: CBX5 (Q61686)
Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Gene: CBX5

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29795351
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Mm			1 191
+	Hs
		800341 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX5_HUMAN (1-191): 2.88e-69: 210: 97.91
+	Hs
		800397 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX5_HUMAN (1-191): 2.88e-69: 210: 97.91
+	Hs
		934721 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX3_HUMAN (1-181): 4.97e-62: 192: 60.22
+	Hs
		1027017 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX3_HUMAN (1-181): 4.97e-62: 192: 60.22
+	Hs
		934657 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX1_HUMAN (26-180): 3.2e-56: 177: 64.74
+	Mm
		935445 H31_MOUSE (1-136): 1.98e-62: 189: 99.27		CBX1_MOUSE (26-180): 3.2e-56: 177: 64.74
+	Hs
		949795 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX1_HUMAN (26-180): 3.2e-56: 177: 64.74
+	Hs
		327837 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX7_HUMAN (11-190): 7.01e-45: 150: 24.31
+	Hs
		327844 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX7_HUMAN (11-190): 7.01e-45: 150: 24.31
+	Hs
		935237 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SUV92_HUMAN (3-127): 4.96e-35: 128: 26.19
+	Hs
		203659 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SUV91_HUMAN (4-120): 2.31e-34: 127: 20.51
+	Hs
		935387 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CDYL_HUMAN (8-159): 2.83e-30: 117: 23.13
+	Hs
		123231 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX4_HUMAN (11-125): 2.1e-27: 109: 25.22
+	Hs
		123254 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX4_HUMAN (11-125): 2.1e-27: 109: 25.22
+	Hs
		934768 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX2_HUMAN (10-109): 8.73e-25: 102: 32.00
+	Hs
		316000 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX6_HUMAN (11-119): 5.27e-25: 101: 25.98
+	Hs
		934987 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CDYL2_HUMAN (18-122): 1.57e-24: 101: 30.70
+	Hs
		1059154 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX2_HUMAN (10-109): 8.73e-25: 102: 32.00
+	Hs
		935259 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX8_HUMAN (11-88): 8.14e-25: 100: 34.62
+	Hs
		316040 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX6_HUMAN (11-119): 5.27e-25: 101: 25.98