HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: MCM6 (Q14566)
DNA replication licensing factor MCM6 (EC 3.6.4.12) (p105MCM)
Gene: MCM6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 821
+	Hs
		934761 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MCM6_HUMAN (1-821): 0: 879: 100.00
+	Mm
		935447 H31_MOUSE (1-136): 3.08e-60: 183: 96.32		MCM6_MOUSE (1-821): 0: 873: 95.86
+	Mm
		952737 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		MCM6_MOUSE (1-821): 0: 873: 95.86
+	Hs
		708603 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MCM5_HUMAN (2-741): 0: 653: 27.42
+	Hs
		708605 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		MCM5_HUMAN (2-741): 0: 653: 27.42
+	Hs
		708661 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		MCM5_HUMAN (2-741): 0: 653: 27.42
+	Hs
		627235 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MCM3_HUMAN (18-813): 0: 639: 25.76
+	Hs
		708861 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MCM7_HUMAN (22-713): 0: 634: 28.88
+	Hs
		708865 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		MCM7_HUMAN (22-713): 0: 634: 28.88
+	Hs
		708415 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MCM4_HUMAN (2-736): 0: 632: 27.70
+	Hs
		708932 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		MCM7_HUMAN (22-713): 0: 634: 28.88
+	Hs
		708421 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		MCM4_HUMAN (2-736): 0: 632: 27.70
+	Hs
		832357 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MCM2_HUMAN (22-732): 0: 628: 28.40
+	Mm
		935446 H31_MOUSE (1-136): 3.08e-60: 183: 96.32		MCM2_MOUSE (22-732): 0: 628: 28.40
+	Hs
		832369 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		MCM2_HUMAN (22-732): 0: 628: 28.40
+	Mm
		952736 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		MCM2_MOUSE (22-732): 0: 628: 28.40
+	Hs
		832495 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		MCM2_HUMAN (22-732): 0: 628: 28.40
+	Mm
		952250 H32_MOUSE (1-136): 5.32e-59: 180: 97.06		MCM2_MOUSE (22-732): 0: 628: 28.40
+	Mm
		935450 H31_MOUSE (1-136): 3.08e-60: 183: 96.32		Q3V122_MOUSE (21-713): 0: 599: 27.76
+	Mm
		952743 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		Q3V122_MOUSE (21-713): 0: 599: 27.76