Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: DOT1L (Q8TEK3)
Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.360) (DOT1-like protein) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4)
Gene: DOT1L

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 36089195
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DOT1~Histone
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0032200 - telomere organization
GO:0032991 - protein-containing complex
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 136
Hs

1 1537
+ Hs
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024