Interactor 1: P91857 (P91857)
small monomeric GTPase (EC 3.6.5.2)
Gene: rab-5

Interactor 2: RME6 (Q9GYH7)
Receptor-mediated endocytosis protein 6
Gene: rme-6

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.740

The method score is based on:

Property Details
Experiments 15895077
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~RasGAP, Ras~VPS9
Common GO terms GO:0005769 - early endosome
GO:0005886 - plasma membrane
GO:0006897 - endocytosis
GO:0030139 - endocytic vesicle
GO:0032794 - GTPase activating protein binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 208
Ce

1 1093
+ Dm
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024