HitPredict

Interactor 1: MCM6 (P97311)
DNA replication licensing factor MCM6 (EC 3.6.4.12) (Mis5 homolog)
Gene: MCM6

Interactor 2: AIRE (Q9Z0E3)
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog)
Gene: AIRE

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20085707
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 821 Mm			1 552
+	Hs
		217480 MCM6_HUMAN (1-821): 0: 900: 95.86		AIRE_HUMAN (17-549): 2.65e-119: 364: 70.28
+	Mm
		831956 MCM5_MOUSE (2-749): 0: 676: 27.36		AIRE_MOUSE (1-552): 2.26e-142: 424: 100.00
+	Mm
		956200 MCM2_MOUSE (10-732): 0: 661: 28.08		AIRE_MOUSE (1-552): 2.26e-142: 424: 100.00
+	Hs
		217452 MCM5_HUMAN (2-749): 0: 681: 27.26		AIRE_HUMAN (17-549): 2.65e-119: 364: 70.28
+	Hs
		217459 MCM2_HUMAN (10-732): 0: 661: 28.08		AIRE_HUMAN (17-549): 2.65e-119: 364: 70.28
+	Hs
		1055555 MCM6_HUMAN (1-821): 0: 900: 95.86		CHD4_HUMAN (66-540): 6.09e-24: 109: 12.50
+	Hs
		1055657 MCM6_HUMAN (1-821): 0: 900: 95.86		TRI33_HUMAN (345-516): 8.78e-15: 79.8: 18.50
+	Hs
		170364 MCM6_HUMAN (1-821): 0: 900: 95.86		TIF1A_HUMAN (407-484): 3.03e-14: 77.9: 26.92
+	Dm
		1359684 MCM6_DROME (11-820): 0: 798: 62.13		KDM5_DROME (428-485): 9.65e-12: 70.2: 18.97
+	Hs
		708618 MCM5_HUMAN (2-749): 0: 681: 27.26		CHD3_HUMAN (32-431): 3.08e-43: 168: 15.17
+	Hs
		627247 MCM3_HUMAN (13-813): 0: 664: 25.87		CHD3_HUMAN (32-431): 3.08e-43: 168: 15.17
+	Hs
		832409 MCM2_HUMAN (10-732): 0: 661: 28.08		CHD3_HUMAN (32-431): 3.08e-43: 168: 15.17
+	Hs
		708880 MCM7_HUMAN (22-732): 0: 622: 28.18		CHD3_HUMAN (32-431): 3.08e-43: 168: 15.17
+	Hs
		627266 MCM3_HUMAN (13-813): 0: 664: 25.87		CHD4_HUMAN (66-540): 6.09e-24: 109: 12.50
+	Hs
		832782 MCM2_HUMAN (10-732): 0: 661: 28.08		TRI33_HUMAN (345-516): 8.78e-15: 79.8: 18.50
+	Hs
		170301 MCM2_HUMAN (10-732): 0: 661: 28.08		TIF1A_HUMAN (407-484): 3.03e-14: 77.9: 26.92
+	Hs
		708544 MCM4_HUMAN (2-738): 0: 659: 26.83		TRI33_HUMAN (345-516): 8.78e-15: 79.8: 18.50
+	Hs
		170275 MCM4_HUMAN (2-738): 0: 659: 26.83		TIF1A_HUMAN (407-484): 3.03e-14: 77.9: 26.92
+	Dm
		1099476 MCM4_DROME (2-743): 0: 641: 27.14		KDM5_DROME (428-485): 9.65e-12: 70.2: 18.97
+	Hs
		170276 MCM7_HUMAN (22-732): 0: 622: 28.18		TIF1A_HUMAN (407-484): 3.03e-14: 77.9: 26.92