Protein: PPLA
Phospholamban (PLB)

Gene: PPLA, PLN
Organism: Homo sapiens
Interactions: 72
UniProt ID: P26678

Gene Ontology (top 5):
GO:0001675 - acrosome assembly
GO:0002026 - regulation of the force of heart contraction
GO:0004857 - enzyme inhibitor activity
GO:0005739 - mitochondrion
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

598008

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

6

3

Small-scale

0.935

High

173861

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

3

3

Small-scale

0.827

High

688373

PPLA
Phospholamban

2

1

Small-scale

0.778

High

688379

DMPK
Myotonin-protein kinase

1

1

Small-scale

0.770

High

688405

EDA
Ectodysplasin-A

6

0

High-throughput

0.710

High

688413

B2L13
Bcl-2-like protein 13

3

0

High-throughput

0.646

High

688391

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

3

0

High-throughput

0.639

High

166866

MGST3
Glutathione S-transferase 3, mitochondrial

2

1

High-throughput

0.606

High

455950

ASGR2
Asialoglycoprotein receptor 2

2

1

High-throughput

0.606

High

688385

STX1A
Syntaxin-1A

2

1

High-throughput

0.606

High

688410

MGST2
Microsomal glutathione S-transferase 2

2

1

High-throughput

0.606

High

688423

TM45A
Transmembrane protein 45A

2

1

High-throughput

0.606

High

688424

CLC2D
C-type lectin domain family 2 member D

2

1

High-throughput

0.606

High

258632

G37L1
G-protein coupled receptor 37-like 1

2

0

High-throughput

0.580

High

328860

RTN3
Reticulon-3

2

0

High-throughput

0.580

High

337072

NPT2B
Sodium-dependent phosphate transport protein 2B

2

0

High-throughput

0.580

High

590246

MUC1
Mucin-1

2

0

High-throughput

0.580

High

688374

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

2

0

High-throughput

0.580

High

688376

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

0

High-throughput

0.580

High

688380

BIK
Bcl-2-interacting killer

2

0

High-throughput

0.580

High

688383

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

2

0

High-throughput

0.580

High

688384

UT2
Urea transporter 2

2

0

High-throughput

0.580

High

688388

TM52B
Transmembrane protein 52B

2

0

High-throughput

0.580

High

688392

MFSD5
Molybdate-anion transporter

2

0

High-throughput

0.580

High

688393

TM205
Transmembrane protein 205

2

0

High-throughput

0.580

High

688394

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

0

High-throughput

0.580

High

688397

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

0

High-throughput

0.580

High

688398

LSME2
Leucine-rich single-pass membrane protein 2

2

0

High-throughput

0.580

High

688399

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.580

High

688400

FNDC9
Fibronectin type III domain-containing protein 9

2

0

High-throughput

0.580

High

688403

GPX8
Probable glutathione peroxidase 8

2

0

High-throughput

0.580

High

688412

T106C
Transmembrane protein 106C

2

0

High-throughput

0.580

High

688414

ELOV4
Very long chain fatty acid elongase 4

2

0

High-throughput

0.580

High

688416

MFF
Mitochondrial fission factor

2

0

High-throughput

0.580

High

688417

IF3M
Translation initiation factor IF-3, mitochondrial

2

0

High-throughput

0.580

High

688418

SACA1
Sperm acrosome membrane-associated protein 1

2

0

High-throughput

0.580

High

688422

SAR1A
Small COPII coat GTPase SAR1A

2

0

High-throughput

0.580

High

230263

CREB3
Cyclic AMP-responsive element-binding protein 3

1

1

High-throughput

0.573

High

688408

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

1

1

High-throughput

0.573

High

142649

SARCO
Sarcolipin

2

0

Small-scale

0.559

High

688375

STX2
Syntaxin-2

2

1

High-throughput

0.553

High

688377

CXA8
Gap junction alpha-8 protein

2

1

High-throughput

0.553

High

688407

TM45B
Transmembrane protein 45B

2

1

High-throughput

0.553

High

3405

A0A0S2Z4U3
Syndecan

1

1

High-throughput

0.515

High

584615

ELN
Elastin

1

1

Small-scale

0.501

High

269905

SDC3
Syndecan-3

1

1

High-throughput

0.481

High

688386

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

0

Small-scale

0.480

High

688404

SRALN
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator ARLN

1

0

Small-scale

0.480

High

688390

TMM31
Transmembrane protein 31

1

0

High-throughput

0.460

High

688425

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

0

High-throughput

0.460

High

688381

SQSTM
Sequestosome-1

1

0

Small-scale

0.458

High

688409

VMP1
Vacuole membrane protein 1

1

0

Small-scale

0.458

High

186466

VA0E1
V-type proton ATPase subunit e 1

2

0

High-throughput

0.316

High

188817

TMPS2
Transmembrane protease serine 2

2

0

High-throughput

0.316

High

337864

CLD7
Claudin-7

2

0

High-throughput

0.316

High

622029

CD53
Leukocyte surface antigen CD53

2

0

High-throughput

0.316

High

688387

AR13B
ADP-ribosylation factor-like protein 13B

2

0

High-throughput

0.316

High

688389

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

688395

CPLX4
Complexin-4

2

0

High-throughput

0.316

High

688396

T179B
Transmembrane protein 179B

2

0

High-throughput

0.316

High

688401

PLPR1
Phospholipid phosphatase-related protein type 1

2

0

High-throughput

0.316

High

688402

GP152
Probable G-protein coupled receptor 152

2

0

High-throughput

0.316

High

688415

MS4A7
Membrane-spanning 4-domains subfamily A member 7

2

0

High-throughput

0.316

High

688419

S39A2
Zinc transporter ZIP2

2

0

High-throughput

0.316

High

688420

SPAG4
Sperm-associated antigen 4 protein

2

0

High-throughput

0.316

High

688421

S35C2
Solute carrier family 35 member C2

2

0

High-throughput

0.316

High

688426

SIT1
Signaling threshold-regulating transmembrane adapter 1

2

0

High-throughput

0.316

High

688406

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

0

High-throughput

0.282

High

688411

TMM79
Transmembrane protein 79

1

0

High-throughput

0.282

High

688382

AQP6
Aquaporin-6

1

0

High-throughput

0.251

Low

688378

EMP3
Epithelial membrane protein 3

1

0

Small-scale

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025