HitPredict

Interactor 1: NRP1 (P97333)
Neuropilin-1 (A5 protein) (CD antigen CD304)
Gene: NRP1

Interactor 2: SEM4C (Q64151)
Semaphorin-4C (M-Sema F) (Semaphorin-C-like 1) (Sema I) (Semaphorin I)
Gene: Sema4c

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	26633812
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CUB~Sema
Common GO terms	GO:0001755 - neural crest cell migration GO:0005886 - plasma membrane GO:0007411 - axon guidance GO:0048843 - negative regulation of axon extension involved in axon guidance GO:0071526 - semaphorin-plexin signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 923 Mm			1 834
+	Mm
		139667 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM3A_MOUSE (10-648): 0: 692: 33.78
+	Mm
		956250 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM3D_MOUSE (4-661): 0: 686: 32.41
+	Mm
		956245 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM4B_MOUSE (29-785): 0: 670: 36.33
+	Hs
		155353 NRP1_HUMAN (1-923): 0: 1064: 93.17		SEM3A_HUMAN (8-648): 0: 687: 33.48
+	Mm
		956246 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM3C_MOUSE (6-718): 0: 666: 28.28
+	Mm
		140339 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM4D_MOUSE (13-717): 0: 659: 39.00
+	Mm
		956241 NRP1_MOUSE (1-923): 0: 1085: 100.00		Q0VGP2_MOUSE (12-733): 0: 654: 32.13
+	Mm
		936363 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM3E_MOUSE (19-653): 0: 652: 31.78
+	Mm
		292032 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM3F_MOUSE (6-739): 0: 635: 27.62
+	Mm
		192796 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM6A_MOUSE (11-813): 0: 616: 24.50
+	Mm
		956257 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM4F_MOUSE (25-790): 0: 612: 33.59
+	Mm
		956248 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM6D_MOUSE (7-775): 0: 573: 24.63
+	Mm
		139663 NRP2_MOUSE (5-923): 0: 898: 44.10		SEM3A_MOUSE (10-648): 0: 692: 33.78
+	Hs
		155470 NRP1_HUMAN (1-923): 0: 1064: 93.17		PLXA1_HUMAN (20-806): 1.61e-157: 506: 15.05
+	Mm
		956255 NRP1_MOUSE (1-923): 0: 1085: 100.00		SEM6C_MOUSE (46-823): 1.16e-156: 483: 25.23
+	Hs
		155209 NRP1_HUMAN (1-923): 0: 1064: 93.17		PLXB1_HUMAN (38-778): 3.23e-155: 502: 17.97
+	Hs
		234430 NRP2_HUMAN (5-923): 0: 913: 44.14		SEM3F_HUMAN (7-739): 0: 643: 27.90
+	Mm
		192660 NRP2_MOUSE (5-923): 0: 898: 44.10		SEM3F_MOUSE (6-739): 0: 635: 27.62
+	Hs
		234447 NRP2_HUMAN (5-923): 0: 913: 44.14		PLXA1_HUMAN (20-806): 1.61e-157: 506: 15.05
+	Hs
		195962 NRP2_HUMAN (5-923): 0: 913: 44.14		PLXB1_HUMAN (38-778): 3.23e-155: 502: 17.97