Interactor 1: CDK2 (P97377)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2)
Gene: CDK2
Interactor 2: CCNE1 (Q61457)
G1/S-specific cyclin-E1
Gene: CCNE1
Species: Mus musculus
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.979 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18356301, 15749021, 12970760, 8769642, 17699765, 15155733, 18635963, 16627785, 8226784, 16102793, 14627988, 19592082, 20150892 |
| Identification Methods | affinity chromatography technology, pull down, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cyclin_C~Pkinase, Cyclin_N~Pkinase |
| Common GO terms | GO:0000082 - G1/S transition of mitotic cell cycle GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005634 - nucleus GO:0005654 - nucleoplasm and 6 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
