HitPredict

Interactor 1: EPAS1 (P97481)
Endothelial PAS domain-containing protein 1 (EPAS-1) (HIF-1-alpha-like factor) (HLF) (mHLF) (HIF-related factor) (HRF) (Hypoxia-inducible factor 2-alpha) (HIF-2-alpha) (HIF2-alpha)
Gene: EPAS1

Interactor 2: BMAL1 (Q9WTL8)
Basic helix-loop-helix ARNT-like protein 1 (Arnt3) (Aryl hydrocarbon receptor nuclear translocator-like protein 1) (Brain and muscle ARNT-like 1)
Gene: BMAL1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 20211142
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~PAS, PAS~PAS, PAS~PAS_11, PAS_11~PAS_11
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
and 8 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 874
Mm

1 632
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024