HitPredict

Interactor 1: RGS14 (P97492)
Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein) (RPIP1)
Gene: RGS14

Interactor 2: MYPT2 (Q8BG95)
Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2)
Gene: Ppp1r12b

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29518331
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0019901 - protein kinase binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 547 Mm			1 976
+	Mm
		956692 RGS14_MOUSE (1-547): 0: 658: 100.00		MYPT1_MOUSE (17-976): 6.12e-93: 319: 43.59
+	Mm
		956615 RGS14_MOUSE (1-547): 0: 658: 100.00		CSKI1_MOUSE (3-192): 1.47e-36: 152: 15.84
+	Mm
		956640 RGS14_MOUSE (1-547): 0: 658: 100.00		ANS1B_MOUSE (1-95): 1.87e-14: 80.2: 21.43
+	Mm
		103597 RGS14_MOUSE (1-547): 0: 658: 100.00		ANK3_MOUSE (221-408): 1.5e-11: 71: 12.38
+	Hs
		170588 AXIN1_HUMAN (1-313): 6.13e-89: 294: 21.12		TNKS1_HUMAN (10-519): 9.06e-61: 228: 13.50
+	Hs
		310109 AXIN2_HUMAN (1-301): 8.87e-58: 208: 18.97		TNKS1_HUMAN (10-519): 9.06e-61: 228: 13.50
+	Hs
		170717 AXIN1_HUMAN (1-313): 6.13e-89: 294: 21.12		TNKS2_HUMAN (210-587): 1.9e-23: 109: 14.18
+	Hs
		1329543 AXIN2_HUMAN (1-301): 8.87e-58: 208: 18.97		TNKS2_HUMAN (210-587): 1.9e-23: 109: 14.18