HitPredict

Interactor 1: DAB2 (P98082)
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Differentially-expressed protein 2)
Gene: DAB2

Interactor 2: FCHO2 (Q0JRZ9)
F-BAR domain only protein 2
Gene: FCHO2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.705

Property	Details
Experiments	28514442, 33961781, 22323290, 27237791
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005905 - clathrin-coated pit GO:0030136 - clathrin-coated vesicle and 1 others more... GO:0048268 - clathrin coat assembly
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 770 Hs			1 810
+	Hs
		147151 DAB2_HUMAN (1-770): 3.91e-90: 301: 100.00		FCHO1_HUMAN (3-810): 0: 567: 43.59
+	Mm
		1142988 ANS1B_MOUSE (12-230): 5.35e-41: 164: 18.67		PACN1_MOUSE (2-405): 1.86e-81: 270: 16.28
+	Hs
		203251 SYNJ1_HUMAN (196-735): 1.47e-19: 96.5: 13.64		PACN1_HUMAN (1-405): 9.99e-82: 270: 16.47
+	Hs
		957211 DAB2_HUMAN (1-770): 3.91e-90: 301: 100.00		SGIP1_HUMAN (234-580): 7.21e-10: 64.7: 25.35
+	Mm
		957144 DAB2_MOUSE (1-770): 1.47e-81: 278: 82.15		NOSTN_MOUSE (12-303): 2.67e-16: 84.5: 17.26
+	Hs
		203262 SYNJ1_HUMAN (196-735): 1.47e-19: 96.5: 13.64		PACN2_HUMAN (7-405): 1.43e-71: 244: 14.72
+	Hs
		203260 SYNJ1_HUMAN (196-735): 1.47e-19: 96.5: 13.64		PACN3_HUMAN (3-405): 1.68e-70: 239: 14.45
+	Dm
		113976 M9PB30_DROME (264-666): 1.41e-09: 64.3: 16.43		M9PB30_DROME (406-618): 2.53e-09: 63.6: 14.80