Interactor 1: SHC1 (P98083)
SHC-transforming protein 1 (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1
Interactor 2: JAK2 (Q62120)
Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)
Gene: JAK2
Species: Mus musculus
Source: dip
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.24 | 1.00 | 0.492 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 7535773 |
| Identification Methods | experimental interaction detection |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FERM_F1~SH2, PK_Tyr_Ser-Thr~SH2, SH2~SH2 |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0008284 - positive regulation of cell population proliferation GO:0035556 - intracellular signal transduction and 2 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
