Interactor 1: PKD1 (P98161)
Polycystin-1 (PC1) (Autosomal dominant polycystic kidney disease 1 protein)
Gene: PKD1
Interactor 2: PKD2 (Q13563)
Polycystin-2 (PC2) (Autosomal dominant polycystic kidney disease type II protein) (Polycystic kidney disease 2 protein) (Polycystwin) (R48321) (Transient receptor potential cation channel subfamily P member 2)
Gene: PKD2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.982 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10097141, 11901144, 9192675, 21126580, 21642537, 19556541, 30093605, 20168298 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation, molecular sieving, static light scattering, nuclear magnetic resonance, 3D electron microscopy |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PKD_channel~PKD_channel, PKD_channel~Polycystin_dom, Polycystin_dom~Polycystin_dom |
| Common GO terms | GO:0001889 - liver development GO:0001892 - embryonic placenta development GO:0002133 - polycystin complex GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum and 27 others more... |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
