Interactor 1: FOXO4 (P98177)
Forkhead box protein O4 (Fork head domain transcription factor AFX1)
Gene: FOXO4

Interactor 2: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.678

The method score is based on:

Property Details
Experiments 18665269, 20874444, 21525355
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019899 - enzyme binding
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 505
Hs

1 491
+ Hs
+ Hs
+ Mm
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024