Protein: CLC4G
C-type lectin domain family 4 member G (Liver and lymph node sinusoidal endothelial cell C-type lectin) (LSECtin)

Gene: CLC4G, CLEC4G
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q6UXB4

Gene Ontology (top 5):
GO:0001618 - virus receptor activity
GO:0002456 - T cell mediated immunity
GO:0002710 - negative regulation of T cell mediated immunity
GO:0005537 - D-mannose binding
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1249710

SIG12
Sialic acid-binding Ig-like lectin 12

2

13

High-throughput

0.783

High

1249715

LRC4C
Leucine-rich repeat-containing protein 4C

2

10

High-throughput

0.783

High

455914

ASGR1
Asialoglycoprotein receptor 1

1

15

High-throughput

0.656

High

932579

PTN5
Tyrosine-protein phosphatase non-receptor type 5

2

8

High-throughput

0.606

High

1249706

CPLX4
Complexin-4

2

1

High-throughput

0.606

High

520892

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

16

Small-scale

0.575

High

618264

CADH2
Cadherin-2

1

15

Small-scale

0.575

High

952907

ACTB
Actin, cytoplasmic 1

1

2

Small-scale

0.575

High

1187472

AR13B
ADP-ribosylation factor-like protein 13B

2

6

High-throughput

0.553

High

1207527

F209A
Protein FAM209A

2

1

High-throughput

0.553

High

839301

MTOR
Serine/threonine-protein kinase mTOR

1

3

Small-scale

0.536

High

1249716

FBX28
F-box only protein 28

1

1

High-throughput

0.489

High

387282

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.486

High

457104

CAN1
Calpain-1 catalytic subunit

1

0

High-throughput

0.486

High

476730

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.486

High

933855

GEM
GTP-binding protein GEM

1

8

High-throughput

0.481

High

360275

COX1
Cytochrome c oxidase subunit 1

1

1

High-throughput

0.464

High

388846

APOH
Beta-2-glycoprotein 1

1

2

High-throughput

0.464

High

581418

CBPN
Carboxypeptidase N catalytic chain

1

2

High-throughput

0.464

High

628627

CAP7
Azurocidin

1

4

High-throughput

0.464

High

1057186

PRDX1
Peroxiredoxin-1

1

2

High-throughput

0.464

High

254166

CTND1
Catenin delta-1

1

3

Small-scale

0.445

High

278111

FLNB
Filamin-B

1

7

Small-scale

0.445

High

283699

GPC4
Glypican-4

1

2

Small-scale

0.445

High

386473

SPTA1
Spectrin alpha chain, erythrocytic 1

1

11

Small-scale

0.445

High

431838

ITB1
Integrin beta-1

1

13

Small-scale

0.445

High

537370

HSP7C
Heat shock cognate 71 kDa protein

1

4

Small-scale

0.445

High

637581

FLNA
Filamin-A

1

7

Small-scale

0.445

High

698790

CALX
Calnexin

1

12

Small-scale

0.445

High

984167

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

4

Small-scale

0.445

High

1159706

OCLN
Occludin

1

1

Small-scale

0.445

High

407813

SHBG
Sex hormone-binding globulin

1

5

High-throughput

0.439

High

639257

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

2

Small-scale

0.439

High

160531

IRS4
Insulin receptor substrate 4

1

0

Small-scale

0.426

High

344723

AP2A1
AP-2 complex subunit alpha-1

1

0

Small-scale

0.426

High

402616

ALDOA
Fructose-bisphosphate aldolase A

1

0

Small-scale

0.426

High

467526

4F2
Amino acid transporter heavy chain SLC3A2

1

0

Small-scale

0.426

High

764844

CTNB1
Catenin beta-1

1

0

Small-scale

0.426

High

997804

CSK21
Casein kinase II subunit alpha

1

0

Small-scale

0.426

High

1249712

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

0

Small-scale

0.426

High

1249717

RBX2
RING-box protein 2

1

5

High-throughput

0.417

High

179220

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

2

Small-scale

0.407

High

252088

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

1

Small-scale

0.407

High

348576

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

1

Small-scale

0.407

High

445563

IF4E
Eukaryotic translation initiation factor 4E

1

1

Small-scale

0.407

High

457506

TBB5
Tubulin beta chain

1

6

Small-scale

0.407

High

483924

HMOX1
Heme oxygenase 1

1

2

Small-scale

0.407

High

621489

HXK1
Hexokinase-1

1

1

Small-scale

0.407

High

634496

LMNB1
Lamin-B1

1

7

Small-scale

0.407

High

866732

CAZA2
F-actin-capping protein subunit alpha-2

1

3

Small-scale

0.407

High

892583

DNLI3
DNA ligase 3

1

2

Small-scale

0.407

High

914094

HXK2
Hexokinase-2

1

1

Small-scale

0.407

High

915117

CAZA1
F-actin-capping protein subunit alpha-1

1

3

Small-scale

0.407

High

996735

TBA1B
Tubulin alpha-1B chain

1

5

Small-scale

0.407

High

997387

TBB4B
Tubulin beta-4B chain

1

6

Small-scale

0.407

High

1008203

PRKDC
DNA-dependent protein kinase catalytic subunit

1

3

Small-scale

0.407

High

1042020

LMNB2
Lamin-B2

1

7

Small-scale

0.407

High

1130079

SMC1A
Structural maintenance of chromosomes protein 1A

1

1

Small-scale

0.407

High

1249704

RFIP1
Rab11 family-interacting protein 1

1

1

Small-scale

0.407

High

1249714

TBB2B
Tubulin beta-2B chain

1

6

Small-scale

0.407

High

1249719

SMC3
Structural maintenance of chromosomes protein 3

1

1

Small-scale

0.407

High

139905

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

2

0

High-throughput

0.316

High

1009799

IN35
Interferon-induced 35 kDa protein

1

0

High-throughput

0.299

High

1102852

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

0

High-throughput

0.299

High

1249707

UN45B
Protein unc-45 homolog B

1

0

High-throughput

0.279

Low

391306

FRIL
Ferritin light chain

1

0

High-throughput

0.265

Low

582343

ARSA
Arylsulfatase A

1

0

High-throughput

0.265

Low

720886

KPYR
Pyruvate kinase PKLR

1

0

High-throughput

0.265

Low

775557

NU214
Nuclear pore complex protein Nup214

1

0

High-throughput

0.265

Low

941190

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.265

Low

1159130

M3K11
Mitogen-activated protein kinase kinase kinase 11

1

0

High-throughput

0.265

Low

1249708

WBP2
WW domain-binding protein 2

1

0

High-throughput

0.265

Low

238543

RAD21
Double-strand-break repair protein rad21 homolog

1

0

Small-scale

0.232

Low

290943

PPM1B
Protein phosphatase 1B

1

0

Small-scale

0.232

Low

365404

PGK1
Phosphoglycerate kinase 1

1

0

Small-scale

0.232

Low

484571

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

Small-scale

0.232

Low

660652

IF4B
Eukaryotic translation initiation factor 4B

1

0

Small-scale

0.232

Low

979015

RS6
Small ribosomal subunit protein eS6

1

0

Small-scale

0.232

Low

1249705

TM10C
tRNA methyltransferase 10 homolog C

1

0

Small-scale

0.232

Low

1249709

PBIR1
PPP2R1A-PPP2R2A-interacting phosphatase regulator 1

1

0

Small-scale

0.232

Low

1249711

VPS35
Vacuolar protein sorting-associated protein 35

1

0

Small-scale

0.232

Low

1249713

G6PC3
Glucose-6-phosphatase 3

1

0

Small-scale

0.232

Low

1249718

UTP16
U3 small nucleolar RNA-associated protein NOL7

1

0

Small-scale

0.232

Low

1249720

RUVB1
RuvB-like 1

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025