HitPredict

Interactor 1: KDPD (P9WGL3)
Sensor protein KdpD (EC 2.7.13.3)
Gene: KDPD

Interactor 2: KDPE (P9WGN1)
Transcriptional regulatory protein KdpE
Gene: KDPE

Species: Mycobacterium tuberculosis H37Rv

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	16844784
Identification Methods	dihydrofolate reductase reconstruction
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HATPase_c~Response_reg, HisKA~Response_reg
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 860 Mt			1 226
+	Ec
		602045 KDPD_ECOLI (14-859): 0: 786: 30.91		KDPE_ECOLI (1-224): 5.34e-72: 220: 49.55
+	Ec
		439475 PHOR_ECOLI (435-854): 1.64e-72: 246: 17.14		PHOB_ECOLI (3-224): 3.53e-76: 230: 32.00
+	Ss
		937545 Q55475_SYNY3 (455-855): 1.15e-66: 229: 19.22		P72948_SYNY3 (1-225): 1.12e-80: 243: 29.31
+	Mx
		1091479 Q1D333_MYXXD (452-856): 6.54e-70: 240: 21.90		Q1DCL7_MYXXD (4-225): 2.02e-76: 231: 39.73
+	Mx
		1091444 Q1D333_MYXXD (452-856): 6.54e-70: 240: 21.90		Q1D1K9_MYXXD (3-225): 1.37e-72: 221: 34.53
+	Mx
		1091475 Q1D333_MYXXD (452-856): 6.54e-70: 240: 21.90		Q1D8M8_MYXXD (2-225): 1.9e-69: 214: 33.63
+	Mx
		1091248 Q1CVV2_MYXXD (456-860): 5.57e-64: 232: 19.04		Q1D1K9_MYXXD (3-225): 1.37e-72: 221: 34.53
+	Mx
		1091447 Q1DDJ8_MYXXD (399-860): 1.52e-65: 230: 18.13		Q1D1K9_MYXXD (3-225): 1.37e-72: 221: 34.53
+	Mx
		1091472 Q1D333_MYXXD (452-856): 6.54e-70: 240: 21.90		Q1D6S6_MYXXD (2-224): 8.23e-67: 206: 33.04
+	Mx
		1091469 Q1D333_MYXXD (452-856): 6.54e-70: 240: 21.90		Q1D334_MYXXD (1-224): 8.02e-66: 204: 36.56
+	Mx
		1091561 Q1DDJ8_MYXXD (399-860): 1.52e-65: 230: 18.13		Q1D8M8_MYXXD (2-225): 1.9e-69: 214: 33.63
+	Ss
		939460 P74622_SYNY3 (565-853): 1.17e-63: 218: 24.74		P74626_SYNY3 (2-225): 1.3e-72: 221: 30.67
+	Ss
		1122356 RPPB_SYNY3 (454-855): 2.96e-67: 233: 18.25		RPPA_SYNY3 (2-224): 1.09e-65: 204: 27.35
+	Mx
		1091371 Q1D333_MYXXD (452-856): 6.54e-70: 240: 21.90		Q1CYI6_MYXXD (1-225): 4.21e-62: 195: 32.90
+	Mx
		1091400 Q1DDJ8_MYXXD (399-860): 1.52e-65: 230: 18.13		Q1CZP3_MYXXD (3-224): 4.19e-66: 205: 30.94
+	Mx
		1091500 Q1D8M1_MYXXD (604-854): 4.28e-58: 217: 30.59		Q1D4T4_MYXXD (2-225): 2.17e-71: 218: 29.26
+	Mx
		1091398 Q1D8M1_MYXXD (604-854): 4.28e-58: 217: 30.59		Q1CZP3_MYXXD (3-224): 4.19e-66: 205: 30.94
+	Ec
		752005 TORS_ECOLI (527-858): 3.75e-62: 228: 20.06		TORR_ECOLI (1-226): 2e-58: 185: 27.59
+	Ss
		937876 Q55783_SYNY3 (531-858): 1.13e-68: 235: 18.81		P73104_SYNY3 (3-213): 2.79e-55: 177: 25.23
+	Ss
		938972 P74015_SYNY3 (592-857): 7.87e-63: 225: 20.79		P74014_SYNY3 (4-112): 1.09e-16: 79.7: 35.71