HitPredict

Interactor 1: CDK17 (Q00537)
Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)
Gene: CDK17

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 523 Hs			1 582
+	Hs
		960373 CDK16_HUMAN (1-513): 1.11e-158: 462: 69.20		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		625477 CDK2_HUMAN (189-484): 1.93e-160: 459: 52.35		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		960098 CDK3_HUMAN (189-492): 3.96e-152: 438: 50.98		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		989681 CDK18_HUMAN (54-522): 1.08e-145: 428: 66.31		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		414946 CDK1_HUMAN (189-478): 5.1e-143: 415: 54.95		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		960291 CDK5_HUMAN (189-479): 3.6e-139: 405: 55.63		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		300640 CDK14_HUMAN (164-520): 5.9e-131: 390: 53.89		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1116470 CDK15_HUMAN (182-513): 9.28e-131: 388: 52.54		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		403088 CDK2_HUMAN (189-484): 1.93e-160: 459: 52.35		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		516362 CDK2_HUMAN (189-484): 1.93e-160: 459: 52.35		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		989704 CDK18_HUMAN (54-522): 1.08e-145: 428: 66.31		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Sc
		565522 PHO85_YEAST (191-475): 2.24e-129: 380: 50.51		LHP1_YEAST (7-270): 1.34e-45: 163: 22.74
+	Sc
		339316 CDK1_YEAST (187-475): 5.75e-129: 379: 50.68		PABP_YEAST (9-243): 8.44e-33: 134: 13.47
+	Dm
		582590 CDK2_DROME (189-484): 2.14e-129: 380: 49.01		SXL_DROME (59-259): 1.13e-24: 107: 20.29
+	Hs
		414931 CDK1_HUMAN (189-478): 5.1e-143: 415: 54.95		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Dm
		114975 M9PE01_DROME (108-506): 2.66e-134: 401: 50.97		LARP_DROME (38-120): 1.58e-13: 76.1: 35.23