Interactor 1: PURA (Q00577)
Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha)
Gene: PURA

Interactor 2: E2F1 (Q01094)
Transcription factor E2F1 (E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1) (Retinoblastoma-binding protein 3) (RBBP-3) (pRB-binding protein E2F-1)
Gene: E2F1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.602

The method score is based on:

Property Details
Experiments 15517862, 10597240
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0140297 - DNA-binding transcription factor binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 322
Hs

1 437
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024