HitPredict

Interactor 1: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Interactor 2: GGA3 (Q9NZ52)
ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3)
Gene: GGA3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11301005
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Alpha_adaptinC2~Clathrin
Common GO terms	GO:0005764 - lysosome GO:0006886 - intracellular protein transport GO:0032991 - protein-containing complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1675 Hs			1 723
+	Hs
		961013 CLH1_HUMAN (1-1675): 0: 3132: 100.00		GGA1_HUMAN (2-723): 1.09e-91: 301: 39.78
+	Hs
		960857 CLH1_HUMAN (1-1675): 0: 3132: 100.00		TM1L2_HUMAN (7-511): 5.58e-88: 287: 21.58
+	Hs
		241163 CLH1_HUMAN (1-1675): 0: 3132: 100.00		TOM1_HUMAN (7-402): 8.19e-85: 278: 22.76
+	Hs
		960908 CLH1_HUMAN (1-1675): 0: 3132: 100.00		STAM1_HUMAN (1-522): 4.18e-75: 254: 17.10
+	Hs
		272801 CLH1_HUMAN (1-1675): 0: 3132: 100.00		TM1L1_HUMAN (6-473): 8.9e-63: 219: 16.50
+	Hs
		159961 CLH1_HUMAN (1-1675): 0: 3132: 100.00		HGS_HUMAN (8-709): 5.07e-58: 212: 13.37
+	Mm
		1148410 CLH1_MOUSE (1-1675): 0: 3131: 99.88		TM1L1_MOUSE (6-438): 8.69e-58: 205: 16.29
+	Hs
		212619 CLH1_HUMAN (1-1675): 0: 3132: 100.00		AP1G1_HUMAN (503-720): 2.89e-51: 193: 26.96
+	Hs
		961012 CLH1_HUMAN (1-1675): 0: 3132: 100.00		GGA2_HUMAN (456-721): 1.1e-25: 114: 34.83
+	Mm
		1148412 CLH1_MOUSE (1-1675): 0: 3131: 99.88		HGS_MOUSE (8-144): 9.66e-09: 60.8: 31.43
+	Dm
		669650 CLH_DROME (1-1663): 0: 2911: 80.17		Q9W329_DROME (9-705): 8.66e-69: 240: 22.06
+	Hs
		241158 CLH2_HUMAN (1-1634): 0: 2869: 85.01		TOM1_HUMAN (7-402): 8.19e-85: 278: 22.76
+	Hs
		863981 CLH2_HUMAN (1-1634): 0: 2869: 85.01		STAM1_HUMAN (1-522): 4.18e-75: 254: 17.10
+	Ce
		712329 CLH_CAEEL (5-1671): 0: 2799: 71.19		Q17796_CAEEL (6-400): 1.98e-66: 235: 14.21
+	Zm
		25357 A0A1D6IQ85_MAIZE (6-1617): 0: 2658: 56.96		C4J1G1_MAIZE (6-585): 1.15e-57: 207: 16.34
+	Sc
		604476 CLH_YEAST (5-1648): 0: 2443: 49.79		GGA1_YEAST (2-425): 1.01e-68: 237: 21.28
+	Sc
		604404 CLH_YEAST (5-1648): 0: 2443: 49.79		GGA2_YEAST (2-437): 2.07e-66: 231: 21.70
+	Sc
		604424 CLH_YEAST (5-1648): 0: 2443: 49.79		VPS27_YEAST (1-595): 9.4e-65: 228: 14.56