Interactor 1: HSF1 (Q00613)
Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1)
Gene: HSF1

Interactor 2: HSF1 (Q00613)
Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1)
Gene: HSF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.915

The method score is based on:

Property Details
Experiments 20098725, 19758120, 29997244, 36339263, 26727490
Identification Methods affinity chromatography technology, pull down, fluorescent resonance energy transfer, molecular sieving
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HSF_DNA-bind~HSF_DNA-bind
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000165 - MAPK cascade
GO:0000776 - kinetochore
GO:0000785 - chromatin
GO:0000791 - euchromatin
and 74 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 529
Hs

1 529
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ At
+ At
+ At
+ Ce
+ Sc
+ At
+ At
+ At
+ Tt
+ At
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024