HitPredict

Interactor 1: NFKB2 (Q00653)
Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10 protein) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2) (Oncogene Lyt-10) (Lyt10) [Cleaved into: Nuclear factor NF-kappa-B p52 subunit]
Gene: NFKB2

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.750

The method score is based on:

Property Details
Experiments 11994270, 18617892, 16303288, 15140882, 25900982, 14676825, 22388891, 14743216
Identification Methods affinity chromatography technology, unspecified method, proximity labelling technology, enzymatic study, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0038061 - non-canonical NF-kappaB signal transduction
GO:0048511 - rhythmic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 900
Hs

1 605
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Last updated: 15 Jul 2024