HitPredict

Interactor 1: NAA20 (P61599)
N-alpha-acetyltransferase 20 (EC 2.3.1.254) (Methionine N-acetyltransferase) (N-acetyltransferase 5) (N-terminal acetyltransferase B complex catalytic subunit NAA20) (N-terminal acetyltransferase B complex catalytic subunit NAT5) (NatB complex subunit NAT5) (NatB catalytic subunit)
Gene: NAA20

Interactor 2: NAA25 (Q14CX7)
N-alpha-acetyltransferase 25, NatB auxiliary subunit (Mitochondrial distribution and morphology protein 20) (N-terminal acetyltransferase B complex subunit MDM20) (NatB complex subunit MDM20) (N-terminal acetyltransferase B complex subunit NAA25) (p120)
Gene: NAA25

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	18570629
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Acetyltransf_1~NatB_MDM20
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031416 - NatB complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 178 Hs			1 972
+	Dm
		1471821 Q9VWF5_DROME (1-178): 2.36e-69: 209: 69.10		NAA25_DROME (12-728): 0: 626: 35.65
+	Dm
		122281 M9PI14_DROME (1-177): 4.55e-67: 204: 67.23		NAA25_DROME (12-728): 0: 626: 35.65
+	Ce
		1170548 Q965S3_CAEEL (1-178): 2.55e-59: 184: 60.11		NAA25_CAEEL (12-710): 0: 565: 27.43
+	Mm
		108274 NAA10_MOUSE (3-162): 5.43e-58: 183: 31.48		G3X8Y3_MOUSE (10-524): 1.56e-127: 409: 12.22
+	Hs
		833678 NAA10_HUMAN (3-162): 2.32e-58: 184: 31.48		NAA15_HUMAN (10-524): 1.72e-127: 408: 12.39
+	Hs
		1412912 NAA11_HUMAN (3-162): 3.67e-57: 180: 33.33		NAA15_HUMAN (10-524): 1.72e-127: 408: 12.39
+	Hs
		1416876 NAA50_HUMAN (2-160): 4.86e-47: 152: 20.00		NAA15_HUMAN (10-524): 1.72e-127: 408: 12.39
+	Sc
		1055423 NAT3_YEAST (1-173): 7.68e-49: 158: 40.61		NAA25_YEAST (16-697): 4.93e-122: 392: 18.79
+	Dm
		1486022 Q9VT75_DROME (3-176): 3.96e-61: 189: 31.64		Q9VWI2_DROME (10-537): 1.79e-107: 356: 11.56
+	Hs
		833641 NAA10_HUMAN (3-162): 2.32e-58: 184: 31.48		NAA16_HUMAN (10-527): 1.46e-106: 352: 11.11
+	Hs
		1236176 NAA11_HUMAN (3-162): 3.67e-57: 180: 33.33		NAA16_HUMAN (10-527): 1.46e-106: 352: 11.11
+	Ca
		1202852 Q5AAR6_CANAL (1-166): 1.35e-52: 167: 42.78		Q5AB99_CANAL (13-674): 8.77e-110: 358: 19.37
+	Dm
		1445610 SAN_DROME (2-164): 1.21e-47: 155: 19.51		Q9VWI2_DROME (10-537): 1.79e-107: 356: 11.56
+	Hs
		1236178 NAA50_HUMAN (2-160): 4.86e-47: 152: 20.00		NAA16_HUMAN (10-527): 1.46e-106: 352: 11.11
+	Sp
		267823 YCPD_SCHPO (1-132): 1.89e-26: 99.7: 16.30		NAT1_SCHPO (10-525): 6.25e-84: 288: 12.39
+	Sc
		456495 ARD1_YEAST (2-157): 2.35e-40: 138: 27.27		NAT1_YEAST (11-359): 5.57e-65: 237: 12.02
+	Sc
		557640 NAT5_YEAST (3-157): 6.32e-31: 112: 14.04		NAT1_YEAST (11-359): 5.57e-65: 237: 12.02