Protein: GFPT1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 1) (Glutamine:fructose-6-phosphate amidotransferase 1) (GFAT 1) (GFAT1) (Hexosephosphate aminotransferase 1)

Gene: GFPT1
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q06210

Gene Ontology (top 5):
GO:0004360 - glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO:0005829 - cytosol
GO:0006002 - fructose 6-phosphate metabolic process
GO:0006047 - UDP-N-acetylglucosamine metabolic process
GO:0006048 - UDP-N-acetylglucosamine biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

296550

GFPT2
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2

2

10

High-throughput

0.811

High

986531

SIR6
NAD-dependent protein deacylase sirtuin-6

3

3

High-throughput

0.656

High

986501

GFPT1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1

1

10

Small-scale

0.647

High

227248

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.584

High

503951

HSP7C
Heat shock cognate 71 kDa protein

2

0

High-throughput

0.559

High

529020

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

871365

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

2

High-throughput

0.536

High

800756

MK08
Mitogen-activated protein kinase 8

1

0

High-throughput

0.518

High

779286

CCNF
Cyclin-F

1

2

High-throughput

0.515

High

986526

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

986551

SMYD2
N-lysine methyltransferase SMYD2

1

0

High-throughput

0.513

High

147514

SOCS6
Suppressor of cytokine signaling 6

1

0

High-throughput

0.493

High

986503

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

1

High-throughput

0.489

High

125397

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

1

High-throughput

0.479

High

133995

DDX3X
ATP-dependent RNA helicase DDX3X

1

2

Small-scale

0.479

High

148709

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

354426

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.479

High

374098

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

377269

GCR
Glucocorticoid receptor

1

2

High-throughput

0.479

High

475656

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

Small-scale

0.479

High

496905

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.479

High

515840

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.479

High

718782

PHB1
Prohibitin 1

1

2

High-throughput

0.479

High

821999

KC1A
Casein kinase I isoform alpha

1

2

High-throughput

0.479

High

908422

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

986504

EP300
Histone acetyltransferase p300

1

5

High-throughput

0.479

High

986506

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

High-throughput

0.479

High

986508

CUL3
Cullin-3

1

4

High-throughput

0.479

High

986512

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.479

High

986525

DCP2
m7GpppN-mRNA hydrolase

1

1

High-throughput

0.479

High

986536

HDAC2
Histone deacetylase 2

1

2

High-throughput

0.479

High

986538

FBXW7
F-box/WD repeat-containing protein 7

1

3

High-throughput

0.479

High

986540

OPTN
Optineurin

1

1

High-throughput

0.479

High

986548

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

986554

HDAC6
Histone deacetylase 6

1

2

High-throughput

0.479

High

986555

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

212395

AAKB2
5'-AMP-activated protein kinase subunit beta-2

1

0

High-throughput

0.458

High

388398

HSPB1
Heat shock protein beta-1

1

0

Small-scale

0.458

High

717021

CTNB1
Catenin beta-1

1

0

High-throughput

0.458

High

742243

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

835689

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.458

High

969634

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

986507

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

986511

CUL7
Cullin-7

1

0

High-throughput

0.458

High

986513

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

986514

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

986516

TECT1
Tectonic-1

1

0

High-throughput

0.458

High

986518

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

986519

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

986523

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

986534

POC5
Centrosomal protein POC5

1

0

High-throughput

0.458

High

986537

REQU
Zinc finger protein ubi-d4

1

0

High-throughput

0.458

High

986539

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.458

High

986541

RN126
E3 ubiquitin-protein ligase RNF126

1

0

High-throughput

0.458

High

986543

TRIM6
Tripartite motif-containing protein 6

1

0

Small-scale

0.458

High

986546

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

986549

ANLN
Anillin

1

0

High-throughput

0.458

High

986553

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

986556

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.458

High

986557

MTMR7
Myotubularin-related protein 7

1

0

High-throughput

0.458

High

708872

MCM7
DNA replication licensing factor MCM7

1

3

Small-scale

0.445

High

986517

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

986502

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.438

High

244331

BRD4
Bromodomain-containing protein 4

1

4

High-throughput

0.437

High

309799

MRP6
ATP-binding cassette sub-family C member 6

1

1

Small-scale

0.437

High

384699

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

552559

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

651025

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

720293

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

738337

BMR1A
Bone morphogenetic protein receptor type-1A

1

1

High-throughput

0.437

High

832393

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.437

High

903157

WDR5
WD repeat-containing protein 5

1

2

High-throughput

0.437

High

986505

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.437

High

986509

CUL4A
Cullin-4A

1

4

High-throughput

0.437

High

986510

DX39B
Spliceosome RNA helicase DDX39B

1

2

Small-scale

0.437

High

986521

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

986547

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

986550

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

3

High-throughput

0.437

High

986544

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.407

High

346600

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.298

High

234504

DSCAM
Cell adhesion molecule DSCAM

1

0

High-throughput

0.282

High

986515

ZN423
Zinc finger protein 423

1

0

High-throughput

0.279

Low

986533

F169B
Protein FAM169BP

1

0

High-throughput

0.279

Low

986542

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

182713

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.249

Low

329667

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

351358

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.249

Low

352079

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

572625

VGFR1
Vascular endothelial growth factor receptor 1

1

0

High-throughput

0.249

Low

785874

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.249

Low

841673

CDK9
Cyclin-dependent kinase 9

1

0

High-throughput

0.249

Low

959364

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

986520

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

986522

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

986524

HOOK3
Protein Hook homolog 3

1

0

High-throughput

0.249

Low

986527

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

986528

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

986529

NIN
Ninein

1

0

High-throughput

0.249

Low

986530

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.249

Low

986532

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

986535

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low

986545

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

986552

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

986558

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

986559

MTCH2
Mitochondrial carrier homolog 2

1

0

High-throughput

0.249

Low

401882

JUN
Transcription factor Jun

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024