Interactor 1: S61A1 (P61619)
Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha-1)
Gene: SEC61A1

Interactor 2: S61A2 (Q9H9S3)
Protein transport protein Sec61 subunit alpha isoform 2 (Sec61 alpha-2)
Gene: SEC61A2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 35575683
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Plug_translocon~SecY
Common GO terms GO:0005048 - signal sequence binding
GO:0005784 - Sec61 translocon complex
GO:0006616 - SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0008320 - protein transmembrane transporter activity
GO:0031204 - post-translational protein targeting to membrane, translocation
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 476
Hs

1 476
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025