Interactor 1: ESMD (Q01071)
Enhancer of split mdelta protein (E(spl)mdelta) (HLH-mdelta) (Split locus enhancer protein mC)
Gene: E(spl)mdelta-HLH

Interactor 2: ESMD (Q01071)
Enhancer of split mdelta protein (E(spl)mdelta) (HLH-mdelta) (Split locus enhancer protein mC)
Gene: E(spl)mdelta-HLH

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.723

The method score is based on:

Property Details
Experiments 9371806, unassigned4
Identification Methods two hybrid, experimental interaction detection
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hairy_orange~Hairy_orange, HLH~HLH
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
and 10 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 173
Dm

1 173
+ Dm
+ Dm
+ Gg
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
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+ Dm
+ Dm
+ Dm

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Last updated: 15 Jul 2024