Interactor 1: PFD3 (P61758)
Prefoldin subunit 3 (HIBBJ46) (von Hippel-Lindau-binding protein 1) (VBP-1) (VHL-binding protein 1)
Gene: VBP1

Interactor 2: PFD4 (Q9NQP4)
Prefoldin subunit 4 (Protein C-1)
Gene: PFDN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 25416956, 28514442, 32296183, 33961781, 31839598, 24981860, unassigned1304, unassigned3799
Identification Methods two hybrid, affinity chromatography technology, cross-linking study, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Prefoldin~Prefoldin_2
Common GO terms GO:0001540 - amyloid-beta binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006457 - protein folding
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 197
Hs

1 134
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025