Protein: PFD3
Prefoldin subunit 3 (Genes involved in microtubule biogenesis protein 2) (Gim complex subunit 2) (GimC subunit 2)

Gene: PFD3, PAC10
Organism: Saccharomyces cerevisiae S288C
Interactions: 161
UniProt ID: P48363

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0006457 - protein folding
GO:0007017 - microtubule-based process
GO:0007021 - tubulin complex assembly
GO:0015631 - tubulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

871561

PFD5
Prefoldin subunit 5

9

4

Small-scale

0.971

High

871534

PFD6
Prefoldin subunit 6

8

2

Small-scale

0.971

High

871546

PFD4
Prefoldin subunit 4

8

2

Small-scale

0.971

High

816722

PFD2
Prefoldin subunit 2

5

4

Small-scale

0.916

High

863641

PFD1
Prefoldin subunit 1

4

0

Small-scale

0.841

High

554023

TCPA
T-complex protein 1 subunit alpha

1

3

Small-scale

0.575

High

527102

HSP72
Heat shock protein SSA2

2

5

High-throughput

0.552

High

871555

PKH3
Serine/threonine-protein kinase PKH3

2

1

High-throughput

0.534

High

871544

TBG
Tubulin gamma chain

1

9

Small-scale

0.515

High

574714

KSS1
Mitogen-activated protein kinase KSS1

1

1

High-throughput

0.501

High

666205

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

0

High-throughput

0.480

High

679847

CDC48
Cell division control protein 48

1

1

High-throughput

0.470

High

579703

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

871580

YP150
Putative serine/threonine-protein kinase YPL150W

1

1

High-throughput

0.457

High

871582

PKH2
Serine/threonine-protein kinase PKH2

1

1

High-throughput

0.457

High

486243

TBA1
Tubulin alpha-1 chain

1

6

Small-scale

0.445

High

524473

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

536145

ARF1
ADP-ribosylation factor 1

1

1

High-throughput

0.445

High

618913

ARF2
ADP-ribosylation factor 2

1

1

High-throughput

0.445

High

751290

BUD2
Inhibitory regulator protein BUD2/CLA2

1

1

High-throughput

0.445

High

762845

TOR1
Serine/threonine-protein kinase TOR1

1

1

High-throughput

0.445

High

793654

ARL1
ADP-ribosylation factor-like protein 1

1

2

High-throughput

0.445

High

815825

BEM2
GTPase-activating protein BEM2/IPL2

1

1

High-throughput

0.445

High

871558

MSH6
DNA mismatch repair protein MSH6

1

1

High-throughput

0.445

High

400069

PUR1
Amidophosphoribosyltransferase

1

0

High-throughput

0.426

High

477588

MYO1
Myosin-1

1

0

High-throughput

0.426

High

545471

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

560730

KIN2
Serine/threonine-protein kinase KIN2

1

0

High-throughput

0.426

High

638068

ISY1
Pre-mRNA-splicing factor ISY1

1

0

High-throughput

0.426

High

657192

GYS1
Glycogen [starch] synthase isoform 1

1

0

High-throughput

0.426

High

665836

KPC1
Protein kinase C-like 1

1

0

High-throughput

0.426

High

668434

PTP1
Tyrosine-protein phosphatase 1

1

0

High-throughput

0.426

High

712809

CHS3
Chitin synthase 3

1

0

High-throughput

0.426

High

719406

PYRX
Orotate phosphoribosyltransferase 2

1

0

High-throughput

0.426

High

738102

MYO4
Myosin-4

1

0

High-throughput

0.426

High

740675

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.426

High

746095

RAD5
DNA repair protein RAD5

1

0

High-throughput

0.426

High

748140

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

0

High-throughput

0.426

High

751756

PRP8
Pre-mRNA-splicing factor 8

1

0

High-throughput

0.426

High

757818

YBF5
Deoxyribonuclease Tat-D

1

0

High-throughput

0.426

High

757895

UBX1
UBX domain-containing protein 1

1

0

High-throughput

0.426

High

763538

ATG19
Autophagy-related protein 19

1

0

High-throughput

0.426

High

783486

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

791913

AAP1
Alanine/arginine aminopeptidase

1

0

High-throughput

0.426

High

797302

APD1
Actin patches distal protein 1

1

0

High-throughput

0.426

High

798191

YB92
5'-deoxynucleotidase YBR242W

1

0

High-throughput

0.426

High

803148

ECM29
Proteasome component ECM29

1

0

High-throughput

0.426

High

815940

PP2C2
Protein phosphatase 2C homolog 2

1

0

High-throughput

0.426

High

824478

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

825719

CSN11
Cop9 signalosome complex subunit 11

1

0

High-throughput

0.426

High

826239

VID28
GID complex subunit 5

1

0

High-throughput

0.426

High

849681

RGD2
Rho-GTPase-activating protein RGD2

1

0

High-throughput

0.426

High

852637

SPO74
Sporulation-specific protein 74

1

0

High-throughput

0.426

High

865469

BFA1
Mitotic check point protein BFA1

1

0

High-throughput

0.426

High

871102

GTO1
Glutathione S-transferase omega-like 1

1

0

High-throughput

0.426

High

871537

SNT2
E3 ubiquitin-protein ligase SNT2

1

0

High-throughput

0.426

High

871540

RTS3
Protein phosphatase type 2A regulatory subunit RTS3

1

0

High-throughput

0.426

High

871545

ATG2
Autophagy-related protein 2

1

0

High-throughput

0.426

High

871547

IDHH
Isocitrate dehydrogenase [NADP]

1

0

High-throughput

0.426

High

871550

SEN1
Helicase SEN1

1

0

High-throughput

0.426

High

871554

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.426

High

871556

VPS60
Vacuolar protein-sorting-associated protein 60

1

0

High-throughput

0.426

High

871560

MYO5
Myosin-5

1

0

High-throughput

0.426

High

871563

RGC1
Regulator of the glycerol channel 1

1

0

High-throughput

0.426

High

871564

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.426

High

871566

SKG3
Protein SKG3

1

0

High-throughput

0.426

High

871577

YO296
Uncharacterized protein YOR296W

1

0

High-throughput

0.426

High

871578

SLF1
Protein SLF1

1

0

High-throughput

0.426

High

871579

AEP3
ATPase expression protein 3

1

0

High-throughput

0.426

High

871583

IQG1
Ras GTPase-activating-like protein IQG1

1

0

High-throughput

0.426

High

871586

HRT3
F-box protein HRT3

1

0

High-throughput

0.426

High

871587

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.426

High

871588

CEX1
Cytoplasmic export protein 1

1

0

High-throughput

0.426

High

454589

TFS2
Transcription elongation factor S-II

1

1

High-throughput

0.407

High

609070

SKI3
Superkiller protein 3

1

1

High-throughput

0.407

High

734339

DGR2
2-deoxy-glucose resistant protein 2

1

6

High-throughput

0.407

High

735348

ERG3
Delta(7)-sterol 5(6)-desaturase ERG3

1

1

High-throughput

0.407

High

781847

SPO14
Phospholipase D1

1

1

High-throughput

0.407

High

793435

ATR
Serine/threonine-protein kinase MEC1

1

1

High-throughput

0.407

High

794193

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

1

High-throughput

0.407

High

808687

SUR2
Sphingolipid C4-hydroxylase SUR2

1

1

High-throughput

0.407

High

864469

MTR4
ATP-dependent RNA helicase DOB1

1

1

High-throughput

0.407

High

871548

ORC1
Origin recognition complex subunit 1

1

2

High-throughput

0.407

High

871552

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

1

High-throughput

0.407

High

577317

NSP1
Nucleoporin NSP1

2

0

High-throughput

0.307

High

871549

ACT
Actin

2

0

Small-scale

0.288

High

800729

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.261

Low

737007

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

707570

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

871551

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

402049

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.232

Low

536039

SEC7
ADP-ribosylation factor guanine nucleotide-exchange factor SEC7

1

0

High-throughput

0.232

Low

550670

SIR4
Regulatory protein SIR4

1

0

High-throughput

0.232

Low

556610

PEP5
E3 ubiquitin-protein ligase PEP5

1

0

High-throughput

0.232

Low

585311

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.232

Low

586474

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.232

Low

596820

ODPX
Pyruvate dehydrogenase complex protein X component, mitochondrial

1

0

High-throughput

0.232

Low

597691

OM45
Mitochondrial outer membrane protein OM45

1

0

High-throughput

0.232

Low

618606

FAS2
Fatty acid synthase subunit alpha

1

0

High-throughput

0.232

Low

672773

SNT1
Probable DNA-binding protein SNT1

1

0

High-throughput

0.232

Low

699418

CIN8
Kinesin-like protein CIN8

1

0

High-throughput

0.232

Low

721691

RF1M
Peptide chain release factor 1, mitochondrial

1

0

High-throughput

0.232

Low

734807

VPH2
Vacuolar ATPase assembly integral membrane protein VPH2

1

0

High-throughput

0.232

Low

735522

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.232

Low

744316

CHD1
Chromo domain-containing protein 1

1

0

High-throughput

0.232

Low

744975

YHH7
UPF0744 protein YSC83

1

0

High-throughput

0.232

Low

745484

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

High-throughput

0.232

Low

747742

SMC1
Structural maintenance of chromosomes protein 1

1

0

High-throughput

0.232

Low

754489

RT05
Small ribosomal subunit protein uS5m

1

0

High-throughput

0.232

Low

757385

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.232

Low

780833

MUD2
Splicing factor MUD2

1

0

High-throughput

0.232

Low

782376

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.232

Low

782536

NU133
Nucleoporin NUP133

1

0

High-throughput

0.232

Low

792661

AP2A
AP-2 complex subunit alpha

1

0

High-throughput

0.232

Low

795749

STU1
Protein STU1

1

0

High-throughput

0.232

Low

796060

DSF2
Protein DSF2

1

0

High-throughput

0.232

Low

796786

FES1
Hsp70 nucleotide exchange factor FES1

1

0

High-throughput

0.232

Low

815420

RS26B
Small ribosomal subunit protein eS26B

1

0

High-throughput

0.232

Low

816638

GTT3
Glutathione transferase 3

1

0

High-throughput

0.232

Low

820473

YNT5
Uncharacterized protein YNL195C

1

0

High-throughput

0.232

Low

823480

NUP82
Nucleoporin NUP82

1

0

High-throughput

0.232

Low

825063

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.232

Low

825659

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.232

Low

828491

SA185
SIT4-associating protein SAP185

1

0

High-throughput

0.232

Low

830122

MSS2
Protein MSS2, mitochondrial

1

0

High-throughput

0.232

Low

830236

RMRP
Ribonuclease MRP protein subunit SNM1

1

0

High-throughput

0.232

Low

836294

BNI1
Protein BNI1

1

0

High-throughput

0.232

Low

853579

FIP1
Pre-mRNA polyadenylation factor FIP1

1

0

High-throughput

0.232

Low

864088

AIM23
Altered inheritance of mitochondria protein 23, mitochondrial

1

0

High-throughput

0.232

Low

864726

BBC1
Myosin tail region-interacting protein MTI1

1

0

High-throughput

0.232

Low

866229

IML1
Vacuolar membrane-associated protein IML1

1

0

High-throughput

0.232

Low

869271

TEA1
TY1 enhancer activator

1

0

High-throughput

0.232

Low

871533

YD183
Uncharacterized protein YDL183C

1

0

High-throughput

0.232

Low

871535

CWH41
Mannosyl-oligosaccharide glucosidase

1

0

High-throughput

0.232

Low

871536

COS12
Protein COS12

1

0

High-throughput

0.232

Low

871538

GUP1
Membrane-bound O-acyltransferase GUP1

1

0

High-throughput

0.232

Low

871539

COG7
Conserved oligomeric Golgi complex subunit 7

1

0

High-throughput

0.232

Low

871541

RT35
Small ribosomal subunit protein mS45

1

0

High-throughput

0.232

Low

871542

SLI1
N-acetyltransferase SLI1

1

0

High-throughput

0.232

Low

871543

SAY1
Steryl acetyl hydrolase 1

1

0

High-throughput

0.232

Low

871553

AAD16
Putative aryl-alcohol dehydrogenase AAD16

1

0

High-throughput

0.232

Low

871557

TCB3
Tricalbin-3

1

0

High-throughput

0.232

Low

871559

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.232

Low

871562

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.232

Low

871565

SEC10
Exocyst complex component SEC10

1

0

High-throughput

0.232

Low

871567

CFT1
Protein CFT1

1

0

High-throughput

0.232

Low

871568

YD306
F-box protein YDR306C

1

0

High-throughput

0.232

Low

871569

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low

871570

IMH1
Golgin IMH1

1

0

High-throughput

0.232

Low

871571

YP078
Uncharacterized protein YPR078C

1

0

High-throughput

0.232

Low

871572

ADY3
Accumulates dyads protein 3

1

0

High-throughput

0.232

Low

871573

IZH3
ADIPOR-like receptor IZH3

1

0

High-throughput

0.232

Low

871574

TLG2
t-SNARE affecting a late Golgi compartment protein 2

1

0

High-throughput

0.232

Low

871575

DIA2
Protein DIA2

1

0

High-throughput

0.232

Low

871576

OSW1
Outer spore wall protein 1

1

0

High-throughput

0.232

Low

871581

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.232

Low

871584

CRC1
Mitochondrial carnitine carrier

1

0

High-throughput

0.232

Low

871585

TFC8
Transcription factor tau 60 kDa subunit

1

0

High-throughput

0.232

Low

871589

RKM4
Ribosomal lysine N-methyltransferase 4

1

0

High-throughput

0.232

Low

871590

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.232

Low

871591

TRS33
Trafficking protein particle complex subunit 33

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025