HitPredict

Interactor 1: TIAR (Q01085)
Nucleolysin TIAR (TIA-1-related protein)
Gene: TIAL1

Interactor 2: DZIP3 (Q86Y13)
E3 ubiquitin-protein ligase DZIP3 (EC 2.3.2.27) (DAZ-interacting protein 3) (RING-type E3 ubiquitin transferase DZIP3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138)
Gene: DZIP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.657

Property	Details
Experiments	28514442, 32460013, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 1208
+	Hs
		148691 TIAR_HUMAN (1-375): 3.87e-98: 298: 100.00		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Hs
		1031362 PABP4_HUMAN (2-288): 4.71e-64: 217: 24.15		RNF43_HUMAN (1104-1206): 7.85e-24: 110: 26.79
+	Hs
		148763 PABP4_HUMAN (2-288): 4.71e-64: 217: 24.15		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Hs
		148894 PAP1L_HUMAN (7-302): 8.64e-62: 210: 21.45		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Hs
		1031433 PABP4_HUMAN (2-288): 4.71e-64: 217: 24.15		CK5P2_HUMAN (522-912): 1.36e-10: 68.1: 10.02
+	Hs
		148334 PABP1_HUMAN (195-285): 4.67e-12: 69.4: 25.77		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Hs
		149282 PABP3_HUMAN (195-285): 3.7e-11: 66.7: 24.74		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Hs
		516652 PABP1_HUMAN (195-285): 4.67e-12: 69.4: 25.77		CK5P2_HUMAN (522-912): 1.36e-10: 68.1: 10.02