Protein: DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain (MHC class II antigen DQB1)

Gene: DQB1, HLA-DQB1
Organism: Homo sapiens
Interactions: 81
UniProt ID: P01920

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0002250 - adaptive immune response
GO:0002503 - peptide antigen assembly with MHC class II protein complex
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

380393

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

4

20

Small-scale

0.908

High

193663

TPSN
Tapasin

1

20

High-throughput

0.691

High

380239

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

20

High-throughput

0.691

High

380606

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

19

High-throughput

0.691

High

380607

CD1A
T-cell surface glycoprotein CD1a

1

19

High-throughput

0.691

High

380608

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

19

High-throughput

0.691

High

380611

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

19

High-throughput

0.691

High

380612

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

1

19

High-throughput

0.691

High

380616

DMB
HLA class II histocompatibility antigen, DM beta chain

1

18

High-throughput

0.691

High

380617

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

19

High-throughput

0.691

High

380623

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

18

High-throughput

0.691

High

380656

SIRPD
Signal-regulatory protein delta

1

1

High-throughput

0.691

High

380665

CLC2D
C-type lectin domain family 2 member D

1

20

High-throughput

0.691

High

380667

BTNL2
Butyrophilin-like protein 2

1

13

High-throughput

0.691

High

380605

HG2A
HLA class II histocompatibility antigen gamma chain

1

6

Small-scale

0.618

High

380661

TMPS4
Transmembrane protease serine 4

1

12

High-throughput

0.618

High

379824

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

18

High-throughput

0.575

High

380510

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

18

High-throughput

0.575

High

61076

T131L
Transmembrane protein 131-like

1

8

High-throughput

0.536

High

173828

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

11

High-throughput

0.536

High

341272

ECEL1
Endothelin-converting enzyme-like 1

1

9

High-throughput

0.536

High

343833

SEM4F
Semaphorin-4F

1

7

High-throughput

0.536

High

380610

ADT1
ADP/ATP translocase 1

1

7

High-throughput

0.536

High

380614

ITA6
Integrin alpha-6

1

4

High-throughput

0.536

High

380618

MA1A1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

1

2

High-throughput

0.536

High

380619

EAA3
Excitatory amino acid transporter 3

1

4

High-throughput

0.536

High

380621

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

1

High-throughput

0.536

High

380625

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

2

High-throughput

0.536

High

380629

NOMO1
BOS complex subunit NOMO1

1

2

High-throughput

0.536

High

380630

PON2
Serum paraoxonase/arylesterase 2

1

4

High-throughput

0.536

High

380633

SGCB
Beta-sarcoglycan

1

2

High-throughput

0.536

High

380635

GXLT1
Glucoside xylosyltransferase 1

1

4

High-throughput

0.536

High

380637

CNNM4
Metal transporter CNNM4

1

9

High-throughput

0.536

High

380638

TBA1A
Tubulin alpha-1A chain

1

8

High-throughput

0.536

High

380641

CNDG2
Condensin-2 complex subunit G2

1

1

High-throughput

0.536

High

380642

TM87A
Transmembrane protein 87A

1

1

High-throughput

0.536

High

380643

MROH1
Maestro heat-like repeat-containing protein family member 1

1

2

High-throughput

0.536

High

380644

CNNM3
Metal transporter CNNM3

1

9

High-throughput

0.536

High

380645

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

9

High-throughput

0.536

High

380648

T106A
Transmembrane protein 106A

1

15

High-throughput

0.536

High

380650

ASIC4
Acid-sensing ion channel 4

1

14

High-throughput

0.536

High

380653

CSTN3
Calsyntenin-3

1

9

High-throughput

0.536

High

380657

HEAT1
HEAT repeat-containing protein 1

1

2

High-throughput

0.536

High

380659

SDF2L
Stromal cell-derived factor 2-like protein 1

1

3

High-throughput

0.536

High

380660

ITM2C
Integral membrane protein 2C

1

7

High-throughput

0.536

High

380662

CC50A
Cell cycle control protein 50A

1

6

High-throughput

0.536

High

380663

FANCI
Fanconi anemia group I protein

1

2

High-throughput

0.536

High

380668

MA1B1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

2

High-throughput

0.536

High

380632

ADIPO
Adiponectin

1

1

High-throughput

0.514

High

380627

MOGS
Mannosyl-oligosaccharide glucosidase

1

0

High-throughput

0.513

High

380646

NICA
Nicastrin

1

0

High-throughput

0.513

High

337160

APOM
Apolipoprotein M

1

3

High-throughput

0.489

High

380609

PSPC
Surfactant protein C

1

7

High-throughput

0.489

High

380613

IDS
Iduronate 2-sulfatase

1

3

High-throughput

0.489

High

380620

DNSL1
Deoxyribonuclease-1-like 1

1

3

High-throughput

0.489

High

380624

SSBP2
Single-stranded DNA-binding protein 2

1

2

High-throughput

0.489

High

380634

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

1

High-throughput

0.489

High

380636

HEAT6
HEAT repeat-containing protein 6

1

2

High-throughput

0.489

High

380639

INT8
Integrator complex subunit 8

1

1

High-throughput

0.489

High

380640

MON2
Protein MON2 homolog

1

9

High-throughput

0.489

High

380649

SARAF
Store-operated calcium entry-associated regulatory factor

1

4

High-throughput

0.489

High

380651

INT4
Integrator complex subunit 4

1

2

High-throughput

0.489

High

380654

T106C
Transmembrane protein 106C

1

15

High-throughput

0.489

High

380655

FACD2
Fanconi anemia group D2 protein

1

9

High-throughput

0.489

High

380658

UD17
UDP-glucuronosyltransferase 1A7

1

7

High-throughput

0.489

High

380631

KCNJ8
ATP-sensitive inward rectifier potassium channel 8

1

2

High-throughput

0.479

High

48482

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.445

High

58784

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

1

High-throughput

0.445

High

380626

SLC31
Amino acid transporter heavy chain SLC3A1

1

7

High-throughput

0.445

High

380669

S22AE
Solute carrier family 22 member 14

1

5

High-throughput

0.445

High

293017

CD123
Translation initiation factor eIF2 assembly protein

1

4

High-throughput

0.437

High

328346

NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

1

1

High-throughput

0.437

High

380615

COT2
COUP transcription factor 2

1

1

High-throughput

0.437

High

380652

CI072
Guanine nucleotide exchange factor C9orf72

1

3

High-throughput

0.437

High

380664

DNJB9
DnaJ homolog subfamily B member 9

1

8

High-throughput

0.437

High

380666

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

1

High-throughput

0.437

High

224460

PI15
Peptidase inhibitor 15

1

0

High-throughput

0.279

Low

380622

NXPH1
Neurexophilin-1

1

0

High-throughput

0.279

Low

380628

DPOD3
DNA polymerase delta subunit 3

1

0

High-throughput

0.279

Low

380647

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.279

Low

380670

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025