HitPredict

Interactor 1: FOXK2 (Q01167)
Forkhead box protein K2 (G/T-mismatch specific binding protein) (nGTBP) (Interleukin enhancer-binding factor 1)
Gene: FOXK2

Interactor 2: ASXL2 (Q76L83)
Putative Polycomb group protein ASXL2 (Additional sex combs-like protein 2)
Gene: ASXL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	25609649, 24748658, 26416890, 27705803, 32669118
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 660 Hs			1 1435
+	Hs
		952829 FOXK1_HUMAN (34-627): 5.33e-81: 273: 53.57		ASXL2_HUMAN (1-1435): 0: 650: 100.00
+	Hs
		1021227 FOXI1_HUMAN (134-513): 1.62e-56: 197: 23.42		ASXL2_HUMAN (1-1435): 0: 650: 100.00
+	Hs
		152626 FOXK2_HUMAN (35-660): 2.35e-129: 397: 100.00		KMT2D_HUMAN (412-1023): 4.42e-14: 80: 13.50
+	Hs
		964248 FOXK2_HUMAN (35-660): 2.35e-129: 397: 100.00		ASXL3_HUMAN (72-1435): 5.5e-14: 79.7: 12.34
+	Hs
		964210 FOXK2_HUMAN (35-660): 2.35e-129: 397: 100.00		ASXL1_HUMAN (333-1435): 1.06e-13: 78.5: 12.31
+	Hs
		952868 FOXK1_HUMAN (34-627): 5.33e-81: 273: 53.57		ASXL3_HUMAN (72-1435): 5.5e-14: 79.7: 12.34
+	Hs
		952832 FOXK1_HUMAN (34-627): 5.33e-81: 273: 53.57		ASXL1_HUMAN (333-1435): 1.06e-13: 78.5: 12.31
+	Hs
		1110385 FX4L6_HUMAN (213-472): 2.78e-54: 193: 30.00		CRBG1_HUMAN (406-1235): 1.71e-32: 140: 12.70
+	Hs
		152637 FOXI1_HUMAN (134-513): 1.62e-56: 197: 23.42		KMT2D_HUMAN (412-1023): 4.42e-14: 80: 13.50
+	Hs
		152638 FOXL1_HUMAN (233-411): 1.42e-53: 189: 34.90		KMT2D_HUMAN (412-1023): 4.42e-14: 80: 13.50
+	Dm
		970538 FD3_DROME (183-374): 5.49e-48: 176: 33.33		Q9VLS7_DROME (362-1082): 5.85e-10: 66.4: 12.21