HitPredict

Interactor 1: FOXK2 (Q01167)
Forkhead box protein K2 (G/T-mismatch specific binding protein) (nGTBP) (Interleukin enhancer-binding factor 1)
Gene: FOXK2

Interactor 2: ASXL1 (Q8IXJ9)
Polycomb group protein ASXL1 (Additional sex combs-like protein 1)
Gene: ASXL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.721

Property	Details
Experiments	25609649, 26416890, 27705803, 32683582, 32669118
Identification Methods	affinity chromatography technology, two hybrid, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 660 Hs			1 1541
+	Hs
		952832 FOXK1_HUMAN (34-627): 5.33e-81: 273: 53.57		ASXL1_HUMAN (1-1541): 0: 2382: 100.00
+	Hs
		964204 FOXK2_HUMAN (35-660): 2.35e-129: 397: 100.00		ASXL2_HUMAN (1474-1541): 1.14e-23: 111: 55.88
+	Hs
		964248 FOXK2_HUMAN (35-660): 2.35e-129: 397: 100.00		ASXL3_HUMAN (363-661): 2.63e-10: 67.9: 25.72
+	Hs
		952829 FOXK1_HUMAN (34-627): 5.33e-81: 273: 53.57		ASXL2_HUMAN (1474-1541): 1.14e-23: 111: 55.88
+	Hs
		952868 FOXK1_HUMAN (34-627): 5.33e-81: 273: 53.57		ASXL3_HUMAN (363-661): 2.63e-10: 67.9: 25.72
+	Hs
		1021227 FOXI1_HUMAN (134-513): 1.62e-56: 197: 23.42		ASXL2_HUMAN (1474-1541): 1.14e-23: 111: 55.88