Interactor 1: CAC1D (Q01668)
Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Voltage-gated calcium channel subunit alpha Cav1.3)
Gene: CACNA1D

Interactor 2: RYR2 (Q92736)
Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)
Gene: RYR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 31461656
Identification Methods fluorescent resonance energy transfer
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ca_chan_IQ~EF-hand_7, EF-hand_7~Ion_trans, Ion_trans~Ion_trans, Ion_trans~RR_TM4-6
Common GO terms GO:0005262 - calcium channel activity
GO:0005886 - plasma membrane
GO:0006816 - calcium ion transport
GO:0030018 - Z disc
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 2161
Hs

1 4967
+ Hs
+ Mm
+ Oc
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Last updated: 15 Jul 2024