Protein: LPIN1
Phosphatidate phosphatase LPIN1 (EC 3.1.3.4) (Lipin-1)

Gene: LPIN1
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q14693

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1131022

LPIN3
Phosphatidate phosphatase LPIN3

3

3

High-throughput

0.855

High

1131020

LPIN2
Phosphatidate phosphatase LPIN2

1

3

High-throughput

0.691

High

1131026

FBW1B
F-box/WD repeat-containing protein 11

4

3

Small-scale

0.672

High

1131027

FBW1A
F-box/WD repeat-containing protein 1A

2

3

Small-scale

0.634

High

966318

1433G
14-3-3 protein gamma

2

13

High-throughput

0.601

High

971531

1433E
14-3-3 protein epsilon

2

2

High-throughput

0.571

High

1025348

CDK6
Cyclin-dependent kinase 6

1

1

Small-scale

0.550

High

245940

KIF1B
Kinesin-like protein KIF1B

1

2

High-throughput

0.515

High

843563

HD
Huntingtin

1

1

High-throughput

0.515

High

987646

GRB2
Growth factor receptor-bound protein 2

1

1

High-throughput

0.515

High

1025098

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.515

High

1131017

GEMI5
Gem-associated protein 5

1

0

High-throughput

0.513

High

1131021

ARRD3
Arrestin domain-containing protein 3

1

0

High-throughput

0.513

High

1131024

PICK1
PRKCA-binding protein

1

0

High-throughput

0.513

High

573475

ENPL
Endoplasmin

1

0

High-throughput

0.493

High

301426

WFS1
Wolframin

1

0

High-throughput

0.493

High

370672

FOS
Protein c-Fos

1

0

High-throughput

0.493

High

415572

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.493

High

479602

DOPO
Dopamine beta-hydroxylase

1

0

High-throughput

0.493

High

557307

SRC
Proto-oncogene tyrosine-protein kinase Src

1

0

High-throughput

0.493

High

570425

GFAP
Glial fibrillary acidic protein

1

0

High-throughput

0.493

High

637518

FLNA
Filamin-A

1

0

High-throughput

0.493

High

705339

GRN
Progranulin

1

0

High-throughput

0.493

High

895323

GATM
Glycine amidinotransferase, mitochondrial

1

0

High-throughput

0.493

High

1026384

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.493

High

1031897

NC2B
Protein Dr1

1

0

High-throughput

0.493

High

1131013

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.493

High

1131019

JPH3
Junctophilin-3

1

0

High-throughput

0.493

High

1131025

ATX10
Ataxin-10

1

0

High-throughput

0.493

High

1131028

RNF11
RING finger protein 11

1

0

High-throughput

0.493

High

1131029

TF3C3
General transcription factor 3C polypeptide 3

1

0

High-throughput

0.493

High

172820

XPO1
Exportin-1

1

3

High-throughput

0.479

High

279164

ULK1
Serine/threonine-protein kinase ULK1

1

2

Small-scale

0.479

High

330970

KI20A
Kinesin-like protein KIF20A

1

3

High-throughput

0.479

High

984116

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

2

High-throughput

0.479

High

1060603

PPARA
Peroxisome proliferator-activated receptor alpha

1

1

Small-scale

0.479

High

1115654

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

4

High-throughput

0.479

High

1131009

NFAC4
Nuclear factor of activated T-cells, cytoplasmic 4

1

1

Small-scale

0.479

High

1131010

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

1131014

WDTC1
WD and tetratricopeptide repeats protein 1

1

1

High-throughput

0.479

High

1131015

COP1
E3 ubiquitin-protein ligase COP1

1

2

High-throughput

0.479

High

1131018

DCAF4
DDB1- and CUL4-associated factor 4

1

2

High-throughput

0.479

High

105937

APRIO
Alternative prion protein

1

0

High-throughput

0.458

High

136896

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.458

High

885776

KC1E
Casein kinase I isoform epsilon

1

0

Small-scale

0.458

High

1112487

CUL1
Cullin-1

1

0

Small-scale

0.458

High

1131011

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1131016

MICA1
[F-actin]-monooxygenase MICAL1

1

0

High-throughput

0.458

High

1131023

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

691009

1433T
14-3-3 protein theta

1

13

High-throughput

0.445

High

729840

1433B
14-3-3 protein beta/alpha

1

13

High-throughput

0.445

High

967730

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

5

High-throughput

0.445

High

1131012

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

2

High-throughput

0.445

High

992175

SKP1
S-phase kinase-associated protein 1

1

0

High-throughput

0.426

High

411938

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025