HitPredict

Interactor 1: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Interactor 2: DAZP1 (Q96EP5)
DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1)
Gene: DAZAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24999758
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 656 Hs			1 407
+	Hs
		318693 EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02		DAZP1_HUMAN (1-407): 2.87e-77: 246: 100.00
+	Hs
		1031411 RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05		PABP4_HUMAN (4-199): 4.69e-37: 144: 21.21
+	Hs
		516620 RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05		PABP1_HUMAN (3-199): 7.08e-34: 135: 20.60
+	Hs
		680441 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		TIA1_HUMAN (1-279): 2.07e-40: 149: 17.75
+	Mm
		857328 EWS_MOUSE (1-656): 4.67e-42: 163: 94.06		TIA1_MOUSE (1-279): 1.06e-40: 150: 17.41
+	Hs
		852117 RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05		ROA3_HUMAN (80-200): 2.59e-28: 116: 30.08
+	Hs
		453508 RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05		ROA1_HUMAN (102-200): 1.27e-27: 114: 30.30
+	Hs
		609978 RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05		ROA2_HUMAN (103-200): 1.83e-25: 107: 32.65
+	Hs
		852019 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		ROA3_HUMAN (80-200): 2.59e-28: 116: 30.08
+	Hs
		453296 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		ROA1_HUMAN (102-200): 1.27e-27: 114: 30.30
+	Hs
		609816 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		ROA2_HUMAN (103-200): 1.83e-25: 107: 32.65
+	Sc
		376785 HRB1_YEAST (241-452): 4.75e-35: 140: 21.76		PABP_YEAST (2-197): 7.84e-37: 143: 21.72
+	Hs
		726795 FUS_HUMAN (55-545): 1.15e-31: 131: 30.35		PABP4_HUMAN (4-199): 4.69e-37: 144: 21.21
+	Hs
		516383 FUS_HUMAN (55-545): 1.15e-31: 131: 30.35		PABP1_HUMAN (3-199): 7.08e-34: 135: 20.60
+	Hs
		726672 FUS_HUMAN (55-545): 1.15e-31: 131: 30.35		ROA3_HUMAN (80-200): 2.59e-28: 116: 30.08
+	Hs
		453189 FUS_HUMAN (55-545): 1.15e-31: 131: 30.35		ROA1_HUMAN (102-200): 1.27e-27: 114: 30.30
+	Hs
		609735 FUS_HUMAN (55-545): 1.15e-31: 131: 30.35		ROA2_HUMAN (103-200): 1.83e-25: 107: 32.65
+	Sc
		376649 GBP2_YEAST (343-453): 3.82e-16: 83.2: 24.56		PABP_YEAST (2-197): 7.84e-37: 143: 21.72
+	Hs
		318604 EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02		TIAR_HUMAN (3-102): 8.48e-09: 59: 14.85
+	Sc
		634002 GBP2_YEAST (343-453): 3.82e-16: 83.2: 24.56		HRP1_YEAST (1-92): 4.32e-16: 82.1: 35.87