Protein: TSN8
Tetraspanin-8 (Tspan-8) (Transmembrane 4 superfamily member 3) (Tumor-associated antigen CO-029)

Gene: TSN8, TSPAN8
Organism: Homo sapiens
Interactions: 77
UniProt ID: P19075

Gene Ontology (top 5):
GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0007283 - spermatogenesis
GO:0009986 - cell surface
GO:0010468 - regulation of gene expression

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

618372

STX2
Syntaxin-2

2

12

High-throughput

0.606

High

618370

TSN8
Tetraspanin-8

1

19

Small-scale

0.590

High

618384

MEP1B
Meprin A subunit beta

1

3

Small-scale

0.586

High

618381

PTC1
Protein patched homolog 1

1

2

Small-scale

0.561

High

618427

S38A7
Sodium-coupled neutral amino acid transporter 7

2

9

High-throughput

0.553

High

139179

UPK2
Uroplakin-2

1

0

High-throughput

0.546

High

62902

POTEF
POTE ankyrin domain family member F

1

2

High-throughput

0.536

High

165524

SCAM3
Secretory carrier-associated membrane protein 3

1

6

High-throughput

0.536

High

184113

RER1
Protein RER1

1

1

High-throughput

0.536

High

229892

ATP9B
Probable phospholipid-transporting ATPase IIB

1

8

High-throughput

0.536

High

255974

S19A2
Thiamine transporter 1

1

4

High-throughput

0.536

High

296904

DGAT1
Diacylglycerol O-acyltransferase 1

1

2

High-throughput

0.536

High

618388

TM63B
Mechanosensitive cation channel TMEM63B

1

2

High-throughput

0.536

High

618389

ZDH20
Palmitoyltransferase ZDHHC20

1

9

High-throughput

0.536

High

618397

SPA12
Serpin A12

1

5

High-throughput

0.536

High

618400

TM87A
Transmembrane protein 87A

1

4

High-throughput

0.536

High

618401

T161B
Transmembrane protein 161B

1

1

High-throughput

0.536

High

618402

CNNM3
Metal transporter CNNM3

1

3

High-throughput

0.536

High

618415

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

1

5

High-throughput

0.536

High

618416

CIB1
Calcium and integrin-binding protein 1

1

1

High-throughput

0.536

High

618418

TMM43
Transmembrane protein 43

1

2

High-throughput

0.536

High

618426

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

15

High-throughput

0.536

High

618376

IST1
IST1 homolog

1

0

High-throughput

0.513

High

618409

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

0

High-throughput

0.513

High

618429

PCYOX
Prenylcysteine oxidase 1

1

0

High-throughput

0.513

High

155546

NEMP1
Nuclear envelope integral membrane protein 1

1

3

High-throughput

0.489

High

212542

GPAA1
GPI-anchor transamidase component GPAA1

1

1

High-throughput

0.489

High

228061

PM34
Peroxisomal membrane protein PMP34

1

1

High-throughput

0.489

High

268980

ABCB7
Iron-sulfur clusters transporter ABCB7, mitochondrial

1

6

High-throughput

0.489

High

618371

ERD21
ER lumen protein-retaining receptor 1

1

1

High-throughput

0.489

High

618378

TAP1
Antigen peptide transporter 1

1

5

High-throughput

0.489

High

618385

ALG11
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

1

4

High-throughput

0.489

High

618386

HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1

1

5

High-throughput

0.489

High

618387

S2552
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A52

1

1

High-throughput

0.489

High

618390

MBOA5
Lysophospholipid acyltransferase 5

1

4

High-throughput

0.489

High

618391

LTMD1
LETM1 domain-containing protein 1

1

1

High-throughput

0.489

High

618393

LCLT1
Lysocardiolipin acyltransferase 1

1

15

High-throughput

0.489

High

618394

UBP34
Ubiquitin carboxyl-terminal hydrolase 34

1

1

High-throughput

0.489

High

618395

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

13

High-throughput

0.489

High

618396

RETR3
Reticulophagy regulator 3

1

7

High-throughput

0.489

High

618398

FITM2
Acyl-coenzyme A diphosphatase FITM2

1

2

High-throughput

0.489

High

618399

F241A
Uncharacterized protein FAM241A

1

2

High-throughput

0.489

High

618403

ZNT7
Zinc transporter 7

1

5

High-throughput

0.489

High

618405

SNX19
Sorting nexin-19

1

7

High-throughput

0.489

High

618406

PIGT
GPI-anchor transamidase component PIGT

1

1

High-throughput

0.489

High

618407

TM186
Transmembrane protein 186

1

4

High-throughput

0.489

High

618408

F241B
Protein FAM241B

1

4

High-throughput

0.489

High

618411

F210B
Protein FAM210B, mitochondrial

1

7

High-throughput

0.489

High

618412

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

1

3

High-throughput

0.489

High

618414

PIGS
GPI-anchor transamidase component PIGS

1

2

High-throughput

0.489

High

618417

PGAP4
GPI-N-acetylgalactosamine transferase PGAP4

1

2

High-throughput

0.489

High

618419

LMA2L
VIP36-like protein

1

2

High-throughput

0.489

High

618420

UN93B
Protein unc-93 homolog B1

1

1

High-throughput

0.489

High

618421

ARV1
Protein ARV1

1

1

High-throughput

0.489

High

618422

REEP4
Receptor expression-enhancing protein 4

1

9

High-throughput

0.489

High

618425

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

1

15

High-throughput

0.489

High

618430

XPO7
Exportin-7

1

1

High-throughput

0.489

High

618431

TELO2
Telomere length regulation protein TEL2 homolog

1

1

High-throughput

0.489

High

618383

SHH
Sonic hedgehog protein

1

0

Small-scale

0.458

High

618375

SC5A3
Sodium/myo-inositol cotransporter

1

4

High-throughput

0.445

High

618428

RBM22
Pre-mRNA-splicing factor RBM22

1

3

High-throughput

0.407

High

168073

TIM23
Mitochondrial import inner membrane translocase subunit Tim23

2

0

High-throughput

0.316

High

618377

LIPR1
Inactive pancreatic lipase-related protein 1

2

0

High-throughput

0.316

High

161320

P5I11
Tumor protein p53-inducible protein 11

1

0

High-throughput

0.279

Low

276944

MPU1
Mannose-P-dolichol utilization defect 1 protein

1

0

High-throughput

0.279

Low

618373

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.279

Low

618374

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

High-throughput

0.279

Low

618379

VAC14
Protein VAC14 homolog

1

0

High-throughput

0.279

Low

618380

MGAT2
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

0

High-throughput

0.279

Low

618382

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.279

Low

618392

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

1

0

High-throughput

0.279

Low

618404

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

618410

S35E1
Solute carrier family 35 member E1

1

0

High-throughput

0.279

Low

618413

NSUN5
28S rRNA

1

0

High-throughput

0.279

Low

618423

S61A2
Protein transport protein Sec61 subunit alpha isoform 2

1

0

High-throughput

0.279

Low

618424

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025