HitPredict

Interactor 1: RYK (Q01887)
Tyrosine-protein kinase RYK (EC 2.7.10.1) (Kinase VIK) (Met-related kinase) (NYK-R)
Gene: RYK

Interactor 2: AFAD (Q9QZQ1)
Afadin (Afadin adherens junction formation factor) (Protein Af-6)
Gene: Afdn

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	10932185
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 594 Mm			1 1820
+	Mm
		546326 NTRK2_MOUSE (79-594): 1.44e-126: 393: 23.32		AFAD_MOUSE (1-1820): 0: 1078: 100.00
+	Mm
		93711 MET_MOUSE (195-589): 1.74e-108: 356: 31.81		E9Q852_MOUSE (1-1820): 0: 1057: 99.12
+	Hs
		411726 LCK_HUMAN (308-589): 8.88e-108: 335: 31.92		KIF14_HUMAN (38-688): 1.86e-87: 319: 14.80
+	Hs
		609482 FGFR3_HUMAN (121-588): 3.16e-141: 430: 28.51		RADIL_HUMAN (830-1106): 1.17e-25: 118: 16.89
+	Hs
		1049964 NTRK3_HUMAN (75-594): 3.41e-140: 429: 23.47		SCRIB_HUMAN (989-1132): 4.28e-22: 106: 27.03
+	Hs
		507995 FGFR1_HUMAN (117-594): 7.47e-136: 417: 26.56		SCRIB_HUMAN (989-1132): 4.28e-22: 106: 27.03
+	Hs
		1020166 NTRK3_HUMAN (75-594): 3.41e-140: 429: 23.47		PTN13_HUMAN (978-1122): 1.44e-17: 92.2: 28.48
+	Hs
		507970 FGFR1_HUMAN (117-594): 7.47e-136: 417: 26.56		PTN13_HUMAN (978-1122): 1.44e-17: 92.2: 28.48
+	Hs
		280018 FGFR3_HUMAN (121-588): 3.16e-141: 430: 28.51		MPDZ_HUMAN (971-1166): 2.93e-13: 77.9: 20.92
+	Hs
		607966 FGFR4_HUMAN (122-591): 5.16e-128: 396: 27.03		SCRIB_HUMAN (989-1132): 4.28e-22: 106: 27.03
+	Hs
		1020168 NTRK2_HUMAN (79-594): 1.23e-125: 390: 23.09		PTN13_HUMAN (978-1122): 1.44e-17: 92.2: 28.48
+	Hs
		441501 MET_HUMAN (233-589): 1.55e-107: 354: 33.77		SCRIB_HUMAN (989-1132): 4.28e-22: 106: 27.03
+	Hs
		872431 EPHA5_HUMAN (201-586): 9.98e-115: 367: 28.46		PTN13_HUMAN (978-1122): 1.44e-17: 92.2: 28.48
+	Hs
		434182 RET_HUMAN (216-586): 5.77e-110: 356: 27.76		PTN13_HUMAN (978-1122): 1.44e-17: 92.2: 28.48
+	Hs
		411718 LCK_HUMAN (308-589): 8.88e-108: 335: 31.92		SCRIB_HUMAN (989-1132): 4.28e-22: 106: 27.03
+	Hs
		411696 LCK_HUMAN (308-589): 8.88e-108: 335: 31.92		PTN13_HUMAN (978-1122): 1.44e-17: 92.2: 28.48
+	Hs
		411905 LCK_HUMAN (308-589): 8.88e-108: 335: 31.92		MYO5A_HUMAN (1343-1817): 5.8e-17: 90: 11.78
+	Hs
		411824 LCK_HUMAN (308-589): 8.88e-108: 335: 31.92		KI16B_HUMAN (1414-1814): 7.24e-11: 69.9: 11.58
+	Hs
		674422 UFO_HUMAN (302-590): 4.01e-56: 205: 36.95		SCRIB_HUMAN (989-1132): 4.28e-22: 106: 27.03
+	Hs
		435639 IGF1R_HUMAN (312-585): 6.11e-51: 191: 34.42		SCRIB_HUMAN (989-1132): 4.28e-22: 106: 27.03