HitPredict

Interactor 1: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Interactor 2: RPN9 (Q04062)
26S proteasome regulatory subunit RPN9 (Proteasome non-ATPase subunit 7)
Gene: RPN9

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.714

Property	Details
Experiments	16554755, 16429126, 37968396, 15117943, 14759368
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0034515 - proteasome storage granule GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 405 Sc			1 393
+	Hs
		907186 PRS8_HUMAN (3-405): 1.36e-129: 380: 73.95		PSD13_HUMAN (6-391): 1.55e-140: 406: 29.74
+	At
		1209889 PRS4A_ARATH (11-395): 5.61e-138: 403: 44.16		PS13B_ARATH (10-391): 1.25e-129: 379: 30.33
+	At
		1247080 PRS4A_ARATH (11-395): 5.61e-138: 403: 44.16		PS13A_ARATH (10-391): 1.32e-128: 376: 30.33
+	Hs
		913368 PRS10_HUMAN (20-402): 2.79e-124: 366: 43.34		PSD13_HUMAN (6-391): 1.55e-140: 406: 29.74
+	Hs
		906947 PRS4_HUMAN (2-395): 3.16e-121: 360: 44.92		PSD13_HUMAN (6-391): 1.55e-140: 406: 29.74
+	Hs
		798783 PRS6B_HUMAN (13-397): 3.38e-118: 351: 41.04		PSD13_HUMAN (6-391): 1.55e-140: 406: 29.74
+	Hs
		730385 PRS7_HUMAN (60-390): 7.87e-110: 331: 51.05		PSD13_HUMAN (6-391): 1.55e-140: 406: 29.74
+	Dm
		186119 PRS8_DROME (1-405): 2.81e-131: 384: 73.83		Q7KMP8_DROME (6-391): 5.26e-119: 352: 31.46
+	Dm
		1181013 Q9W414_DROME (1-402): 3.17e-123: 364: 43.28		Q7KMP8_DROME (6-391): 5.26e-119: 352: 31.46
+	Sc
		771737 PRS4_YEAST (72-395): 3.99e-106: 321: 49.85		RPN9_YEAST (1-393): 7.16e-133: 387: 100.00
+	Sc
		703958 PRS7_YEAST (83-391): 1.16e-104: 318: 51.78		RPN9_YEAST (1-393): 7.16e-133: 387: 100.00
+	Dm
		1181000 Q9V405_DROME (5-397): 1.09e-118: 352: 39.50		Q7KMP8_DROME (6-391): 5.26e-119: 352: 31.46
+	Dm
		820483 PRS4_DROME (2-395): 3.49e-118: 352: 43.40		Q7KMP8_DROME (6-391): 5.26e-119: 352: 31.46
+	Dm
		1180989 Q7KMQ0_DROME (60-390): 1.44e-108: 327: 51.05		Q7KMP8_DROME (6-391): 5.26e-119: 352: 31.46
+	Hs
		897226 PRS8_HUMAN (3-405): 1.36e-129: 380: 73.95		CSN2_HUMAN (44-384): 2.02e-80: 255: 17.15
+	Hs
		897225 PRS4_HUMAN (2-395): 3.16e-121: 360: 44.92		CSN2_HUMAN (44-384): 2.02e-80: 255: 17.15