HitPredict

Interactor 1: ROR1 (Q01973)
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (Neurotrophic tyrosine kinase, receptor-related 1)
Gene: ROR1

Interactor 2: DUS18 (Q8NEJ0)
Dual specificity protein phosphatase 18 (EC 3.1.3.16) (EC 3.1.3.48) (Low molecular weight dual specificity phosphatase 20) (LMW-DSP20)
Gene: DUSP18

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	28065597
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 937 Hs			1 188
+	Hs
		304949 ROR1_HUMAN (30-937): 0: 775: 100.00		DUS14_HUMAN (9-187): 1.02e-74: 224: 50.28
+	Hs
		968338 ROR1_HUMAN (30-937): 0: 775: 100.00		DUS21_HUMAN (11-188): 4.46e-68: 207: 71.35
+	Hs
		968326 ROR1_HUMAN (30-937): 0: 775: 100.00		DUS19_HUMAN (4-171): 4.85e-60: 188: 30.00
+	Hs
		968315 ROR1_HUMAN (30-937): 0: 775: 100.00		DUS29_HUMAN (15-158): 1.69e-53: 171: 33.55
+	Hs
		968327 ROR1_HUMAN (30-937): 0: 775: 100.00		STYX_HUMAN (15-169): 1.62e-53: 171: 27.78
+	Hs
		968435 ROR2_HUMAN (1-936): 0: 665: 55.33		DUS18_HUMAN (1-188): 1.94e-77: 231: 100.00
+	Hs
		304950 ROR2_HUMAN (1-936): 0: 665: 55.33		DUS14_HUMAN (9-187): 1.02e-74: 224: 50.28
+	Hs
		659272 ROR2_HUMAN (1-936): 0: 665: 55.33		DUS1_HUMAN (5-177): 2.45e-66: 208: 34.10
+	Hs
		968484 ROR2_HUMAN (1-936): 0: 665: 55.33		DUS21_HUMAN (11-188): 4.46e-68: 207: 71.35
+	Hs
		968391 ROR2_HUMAN (1-936): 0: 665: 55.33		DUS6_HUMAN (5-162): 3.18e-61: 196: 29.38
+	Hs
		968440 ROR2_HUMAN (1-936): 0: 665: 55.33		DUS19_HUMAN (4-171): 4.85e-60: 188: 30.00
+	Hs
		968407 ROR2_HUMAN (1-936): 0: 665: 55.33		DUS29_HUMAN (15-158): 1.69e-53: 171: 33.55
+	Hs
		968442 ROR2_HUMAN (1-936): 0: 665: 55.33		STYX_HUMAN (15-169): 1.62e-53: 171: 27.78
+	Hs
		1070986 ERBB4_HUMAN (113-932): 1.7e-142: 458: 18.75		DUS18_HUMAN (1-188): 1.94e-77: 231: 100.00
+	Hs
		169190 MUSK_HUMAN (30-758): 2.24e-169: 517: 26.91		STYX_HUMAN (15-169): 1.62e-53: 171: 27.78
+	Hs
		304961 ERBB4_HUMAN (113-932): 1.7e-142: 458: 18.75		DUS14_HUMAN (9-187): 1.02e-74: 224: 50.28
+	Hs
		729673 VGFR2_HUMAN (38-911): 4.89e-150: 480: 16.41		DUS19_HUMAN (4-171): 4.85e-60: 188: 30.00
+	Hs
		1070972 ERBB4_HUMAN (113-932): 1.7e-142: 458: 18.75		DUS6_HUMAN (5-162): 3.18e-61: 196: 29.38
+	Hs
		729674 VGFR2_HUMAN (38-911): 4.89e-150: 480: 16.41		STYX_HUMAN (15-169): 1.62e-53: 171: 27.78
+	Hs
		1070988 ERBB4_HUMAN (113-932): 1.7e-142: 458: 18.75		DUS19_HUMAN (4-171): 4.85e-60: 188: 30.00