HitPredict

Interactor 1: DSC2 (Q02487)
Desmocollin-2 (Cadherin family member 2) (Desmocollin-3) (Desmosomal glycoprotein II) (Desmosomal glycoprotein III)
Gene: DSC2

Interactor 2: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 901 Hs			1 236
+	Hs
		971029 DSC2_HUMAN (1-901): 0: 855: 100.00		RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48
+	Hs
		950934 DSC2_HUMAN (1-901): 0: 855: 100.00		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		925210 DSC2_HUMAN (1-901): 0: 855: 100.00		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		892326 DSC2_HUMAN (1-901): 0: 855: 100.00		RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00
+	Hs
		564486 DSC2_HUMAN (1-901): 0: 855: 100.00		RHOQ_HUMAN (23-236): 1.99e-73: 223: 50.00
+	Hs
		545331 DSC2_HUMAN (1-901): 0: 855: 100.00		RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43
+	Hs
		900393 DSC2_HUMAN (1-901): 0: 855: 100.00		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		1055834 DSC3_HUMAN (1-901): 0: 806: 66.70		RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48
+	Hs
		893916 DSC2_HUMAN (1-901): 0: 855: 100.00		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		971065 DSC2_HUMAN (1-901): 0: 855: 100.00		RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27
+	Hs
		564530 DSC3_HUMAN (1-901): 0: 806: 66.70		RHOQ_HUMAN (23-236): 1.99e-73: 223: 50.00
+	Hs
		900472 DSC3_HUMAN (1-901): 0: 806: 66.70		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		894012 DSC3_HUMAN (1-901): 0: 806: 66.70		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		1183625 PCDG4_HUMAN (1-852): 0: 737: 17.46		RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48
+	Hs
		1055855 DSC3_HUMAN (1-901): 0: 806: 66.70		RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27
+	Hs
		521847 CADH1_HUMAN (28-897): 0: 714: 28.09		RAB1A_HUMAN (21-234): 6.38e-76: 229: 20.55
+	Hs
		521840 CADH1_HUMAN (28-897): 0: 714: 28.09		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		521837 CADH1_HUMAN (28-897): 0: 714: 28.09		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		606304 CADH3_HUMAN (7-897): 0: 635: 27.50		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		893915 DSG1_HUMAN (130-573): 2.65e-65: 239: 33.18		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39